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Efficacy of hydroxychloroquine in improving pregnancy outcomes in women with systemic lupus erythematosus and antiphospholipid syndrome

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Women with antiphospholipid syndrome (APS) are at increased risk of thrombosis and pregnancy complications, such as recurrent early miscarriage and hypertensive disorders during pregnancy

Patient's pregnancy history:

Case study: A 35-year-old pregnant woman (4th gestation, 1st pregnancy) with SLE, lupus nephritis, and APS presents at 6 weeks of gestation (GW

Changes in blood pressure and blood sampling data:

This case of refractory APS with SLE was successfully treated with HCQ, LDA, therapeutic doses of UFH, prednisolone (PSL), tacrolimus

In patients with APS and previous pregnancy failure who have received standard therapy, HCQ

Overall, HCQ may help improve pregnancy outcomes in patients who have failed a previous pregnancy and are receiving routine treatment with current APS

References: Takaki Y, Daimon A, Nunode M, Tanaka T, Fujita D, Ohmichi M.

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