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    Home > Active Ingredient News > Drugs Articles > Efficacy and effects of chlorpheniramine and precautions

    Efficacy and effects of chlorpheniramine and precautions

    • Last Update: 2022-09-14
    • Source: Internet
    • Author: User
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    Chlorpheniramine APIs are 2-[p-chloro-α-[2-(dimethylamino)ethyl]phenyl]pyridine maleate
    .

    According to the calculation of dried products, the inclusion of C16H19ClN2•C4H4O4 shall not be less than 98.
    5%.

    It is an antihistamine API
    .

    This product is a white crystalline powder; Odorless
    .

    It is easily soluble
    in water or ethanol.

    Store under shaded, sealed conditions
    .

    API name: Chlorpheniramine Maleate alias: Chloropheniramine maleate, chlorpheniramine maleate, chlorpheniramine, chlorpheniramine, chlortramidone main indications: rhinitis, skin and mucosal hypersensitivity and other main drug contraindications: allergies and other prohibited dosage forms: tablets, injections, drop pills Adverse reactions: e heart, epigastric discomfort or stomach pain Chemical formula: C20H23ClN2O4 Molecular weight: 390.
    861 outside View: White crystalline solid or white powder CAS registration number: 113-92-8EINECS registration number: 204-037-5 melting point: 130 to 135 °C boiling point: 379 °C flash point: 183 °C density: 1.
    2 g /cm³.

    Chlorpheniramine tablets, white tablets, are suitable for skin allergies: urticaria, eczema, dermatitis, drug eruptions, pruritus, neurodermatitis, insect bites, solar dermatitis, can also be used for allergic rhinitis, drug and food allergies
    .

    The main adverse reactions were drowsiness, thirst, polyuria, sore throat, drowsiness, feelings of weakness, palpitations, ecchymosis of the skin, and bleeding tendencies
    .

    Chlorpheniramine injection is a colorless clear liquid, the use of intramuscular injection, 5 to 20 mg at a time, 5 to 10 minutes after intramuscular injection onset
    .

    Plasma protein binding rate is about 72%.

    t1/2 is 12 to 15 hours, mainly metabolized by the liver, and the intermediate metabolites have no pharmacological activity
    .

    Metabolites and unmetabolized drugs are excreted mainly through the kidneys
    .

    Adverse reactions are drowsiness, fatigue, fatigue, dry mouth, nose and throat, viscous sputum, which can cause local irritation at the injection site and transient hypotension, and rarely skin ecchymosis and bleeding tendencies
    .

    Chlorpheniramine drop pills are white or white-like drop pills, each containing the main ingredient is chlorpheniramine 4 mg, the dosage is oral: adults 1 pill each time, 3 times a day; Chlorpheniramine for skin allergies Dosage of chlorpheniramine caused by skin allergies is as follows: 1, general adults 4 mg, 3 times a day; 2, children should be reduced, can not use the amount of adults
    .

    The duration of use can generally be used for a week, some patients are chronic urticaria, eating for half a month or even a month
    .

    It is basically not used this way, but it is cheap and is still used in remote areas
    .

    Now they all use a new generation of antihistamines
    such as Karritan.

    These antihistamines must be used under the guidance of a doctor, as each drug has its contraindications and precautions
    .

    What are the precautions for the use of chlorpheniramine Tablets It is recommended not to take it before doing fine movements, such as driving, such as some construction workers going to the construction site, ascending, may pose a risk
    to themselves and others.

    If the allergy is not too serious, it can be taken at night, and long-acting anti-allergic drugs can be used during the day, which may be safer for patients and can also control the symptoms
    of allergies.

    In spring and autumn, many flowers have more pollen, allergies will occur more often, and chlorpheniramine has become a commonly used drug
    .

    It is recommended that before taking chlorpheniramine, it is necessary to understand the pharmacological characteristics, occasionally use a use can, the degree of drowsiness needs to be understood, do not take this drug before doing fine movements
    .

    Chlorpheniramine tablets adversely respond to diphenhydramine, but are weaker
    .

    Chlorpheniramine can induce epilepsy, so it is contraindicated
    in patients with a history of epilepsy.

    It is not advisable to drive a vehicle or perform highly concentrated work during the
    medication.

    Can chlorpheniramine cure insomnia?

    Chlorpheniramine is a clinical generation of antiallergic drugs with antihistamine effects
    .

    It is mainly used for the treatment of allergic dermatitis, eczema and a series of diseases
    including skin itching.

    Clinically found that its side effects can cause drowsiness, so insomnia symptoms cannot be treated
    .

    According to statistics, there are currently fewer patients using chlorpheniramine, especially those who drive cars, who are not suitable for chlorpheniramine
    .

    API price of national medicine quasi word chlorpheniramine
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