Effects of delirium and perioperative stroke on long-term outcomes in patients with high-scoring literature reading and surgical aortic valve replacement

The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement

Effects of delirium and perioperative stroke after surgical aortic valve replacement on long-term outcomes in patients

By Dani & Miao & Cat

Abstract

The effect of stroke and delirium on discharge cognition and health outcomes in patients with surgical aortic valve replacement (SAVR) is unclear
.

Therefore, we aim to investigate the effects
of perioperative stroke and delirium on patient-centered health outcomes at 90 days postoperatively.

Methods: SAVR patients (N=383) (41% who also underwent coronary bypass grafting) were enrolled to undergo neurological function and delirium assessment at 1, 3, and 7 days after surgery, and MRI examination
at 7 days.

Outcomes included a 90-day change in functional levels and neurocognitive decline compared to preoperative changes
.

Results: 25 (6.
6%) patients had clinical stroke and 103 (28.
5%) developed delirium
.

Perioperative stroke patients and delirium patients (HR, 0.
68; 95% [CI]:0.
54-0.
86; P 1/4.
001) experienced a longer hospital stay (HR, 0.
62; 95%[CI]:0.
42-0.
94; P 1/4.
02) Patients with delirium (HR, 0.
68; 95%[CI]:0.
54-0.
86; P ¼ .
001)
。
Stroke patients with 90 days were more likely to score on the modified Rankin scale >2, [OR], 5.
9; 95%[CI]:1.
7-20.
1; P 1/4.
01), more depressed (OR, 5.
3; 95% [CI]:1.
6-17.
3; P 1/4 .
006), lower adjusted mean difference P 1/4 .
08), postoperative cognitive decline (OR, 7.
8; 95% [CI]:2.
3-26.
4; P ¼ .
001)
。

Figure&Table

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