Effect of Perilla Seed Extract on performance and immune function of piglets

In recent years, Perilla frutescens has been used as feed additive to breed animals with good effect Especially, the feed additive of perilla seed extract approved by the Ministry of agriculture has the functions of promoting animal growth, improving production performance, improving the quality of animal products, preventing and curing diseases, etc In this study, the effects of the feed additive of perilla seed plant extract on the performance and immune function of piglets were studied Materials and methods 45 healthy weaned piglets with an average body weight of 9.5kg were randomly divided into 3 groups according to the principle of similar body weight and the same sex ratio One control group (a) and two test groups (B, c) were set up in the experiment Each treatment group had three repetitions and each repetition had five pigs The control group (a) was fed with basic diet, and the two experimental groups (B, c) were fed with 0.01% chlortetracycline and 0.02% perilla seed extract feed additives respectively From the beginning of the experiment, the mental state, diet, defecation and death of piglets were observed and recorded every day Results compared with the control group A, the average daily gain of group B and group C increased by 11.37% and 20.70% respectively, and the average daily gain of group C increased by 8.38% compared with group B The results showed that the average daily gain of piglets could reach a high level by adding the feed additive of perilla seed extract Compared with the control group A, the feed to weight ratio of group B and C decreased by 4.74% and 9.57% (P The diarrhea rate of experimental group C and experimental group B was significantly lower than that of control group A, 30.40% and 27.15% lower respectively (P < 0.01); the diarrhea rate of experimental group B was 4.46% lower than that of experimental group C (P > 0.05) The results showed that the addition of perilla seed extract and chlortetracycline could significantly reduce the diarrhea rate of piglets, but there was no significant difference between the addition of perilla seed extract and chlortetracycline Effect of Perilla Seed Extract on serum biochemical indexes of piglets the total protein content of piglets in test group C increased by 14.16% compared with control group A, 10.76% compared with test group B (P < 0.01), and the total protein content of piglets in test group B increased by 3.07% compared with control group A (P > 0.05) The content of serum albumin in group C was higher than that in group A and group B to some extent, in which group C was 16.00% higher than that in group A and 10.61% higher than that in group B (P < 0.01) Compared with control group A and test group B, the content of serum globulin in test group C increased by 11.77% and 10.97%, respectively (P < 0.05) It can be seen from the analysis results that adding chlortetracycline has no significant effect on the serum protein content and composition of piglets, but adding perilla seed extract can significantly improve the serum total protein, albumin and globulin content of piglets Compared with control group A and test group B, the content of blood urea nitrogen in test group C decreased by 17.20% and 12.81% (P < 0.05), which reflected the situation of protein metabolism and stress to some extent The results showed that the content of blood urea nitrogen in serum decreased, which indicated that adding perilla seed extract additive in diet could improve the utilization rate of nitrogen in feed and promote the deposition of nitrogen in vivo Insulin (INS) is an important hormone to promote the production of glycogen and the regulation of protein synthesis and metabolism in vivo, which can effectively promote protein synthesis and inhibit protein degradation in cells The effect of perilla seed extract additive on serum insulin level of piglets: compared with control group A, test group C increased by 8.66% (P < 0.05), compared with test group B, increased by 11.66%, the difference was significant (P < 0.05), but the difference between test group B and control group a was not significant (P > 0.05) Effect of Perilla Seed Extract on serum immunoglobulin of piglets Results: the content of serum immunoglobulin in experimental group C was 12.9% (P < 0.05) higher than that in control group A and B, 27.27% (P < 0.05) higher than that in experimental group B; the content of serum IgA in experimental group C was 4% higher than that in control group A and experimental group B, with no significant difference (P > 0.05); the content of serum IgM in each treatment group was the same The results showed that perilla seed extract had significant effect on serum immunoglobulin G and a in piglets.