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ECLIPSE study: the efficacy of cryoablation in the treatment of metastatic lung tumors

 Last Update: 2021-12-03
 Source: Internet
 Author: User

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The Phase 2 results of the SOLSTICE study reported the efficacy of cryoablation (CA) in the treatment of lung metastases
.

However, there is still a lack of data on local tumor control and long-term survival

The Phase 2 results of the SOLSTICE study reported the efficacy of cryoablation (CA) in the treatment of lung metastases

The ECLIPSE study published by the Journal of Thoracic Oncology evaluated the feasibility and effectiveness of CA for local tumor control in patients with metastatic lung disease during a 5-year follow-up

ECLIPSE is a prospective, multi-center, single-arm study that included patients with 1 to 5 lung metastases (each metastasis less than or equal to 3.
5 cm in diameter) and receiving CA treatment, followed up for 5 years
.

The primary end point was local tumor control, which was defined as no increase of 20% or more in the diameter of the local ablation zone measured at 6, 12, 24, 36, 48, and 60 months after treatment.

ECLIPSE is a prospective, multi-center, single-arm study that included patients with 1 to 5 lung metastases (each metastasis less than or equal to 3.

The study included 40 patients from 4 research centers (3 in the United States and 1 in Europe)

Studies have shown that cryoablation is an effective method for long-term local tumor control in patients with metastatic lung tumors
.

The 5-year cancer-specific survival rate and overall survival rate are higher than many other local treatments, including surgical resection

Studies have shown that cryoablation is an effective method for long-term local tumor control in patients with metastatic lung tumors

Original source:

Thierry de Baère, David Woodrum, et al, The ECLIPSE Study: Efficacy of Cryoablation on Metastatic Lung T umors With a 5-Year Follow-Up , Journal of Thoracic Oncology, 2021, https://doi.

The ECLIPSE Study: Efficacy of Cryoablation on Metastatic Lung T umors With a 5-Year Follow-Up

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