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In a recent study published in Nature Communications, a team of researchers from the University of Texas at San Antonio's Center for Health Sciences reported that specific chemicals in the brain may be the cause of difficulty concentrating after drinking alcohol.
study's co-author, Martin Paukert, M.D., an assistant professor of cell and integrated physiology at the San Antonio Health Science Center.
"When we want to focus on something, or when we get up from a chair and start to move, the brain core releases methamphetrine, which is secreted by a brain structure called blue spots, and drinking alcohol suppresses this signal in the brain."
", scientists didn't know what would happen next.
the study, Dr. Paukert and his team used dual photon imaging to study live animals in real time.
they found that epinephrine was attached to the subjects of Bergman's glial cells.
this can lead to elevated calcium in these cells.
glial cells are astrological glial cells (guardian or supporting cells) in the small brain.
Paukert said: "Our study is the first to describe the direct binding of epinephrine in mammals to bergman's glial binds and activates them by increasing calcium.
" researchers focused on Bergman's glial cells and demonstrated that the same phenomenon occurs in cortical star-shaped glial cells.
alcoholism is likely to inhibit calcium activation of the entire brain's alert-dependent astrogenic glial cells," said Paukert, an executive at the center of the study.
" people lose their balance when affected.
researchers thought the discovery of calcium elevation inhibition in Bergman's glial cells could explain this.
but that's not the case.
Paukert said:
Insuring calcium in Bergman's glial cells is not important for motion coordination, which is somewhat surprising because the role of the cee brain in motion control is well known.
, however, our findings are consistent with the current view that the small brain also plays a key role in non-motor function, and that astrogenic glial cells not only support the basic maintenance of the brain, but are also actively involved in cognitive function.
Dr Manzoor Bhat, co-author of the study and professor and chair of cell and integrated physiology at the San Antonio Health Science Center, said: "The great thing about this study is that researchers used advanced dual photon imaging technology to conduct real-time studies of living animals.
these findings will open up new ways to define brain circuits that ultimately determine a person's alertness state and how the chemicals that interfere with these circuits inhibit the brain's inherent alertness system.
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