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Obstructive sleep apnea (OSA) is a widespread but often underdiagnosed respiratory disorder characterized by recurrent upper airway obstruction during sleep
.
About 5% of the general population experience OSA; in the 30-60 age group, the prevalence is 9% in women and 9% in men24%
Obstructive Sleep Apnea (OSA) DiagnosisPeople with a family history of OSA, obesity, high blood pressure , menopause, smoking, and alcohol consumption are at higher risk for developing OSA
According to the American College of Obstetricians and Gynecologists (ACOG), infertility is the inability to conceive after 1 year or more of routine unprotected intercourse
Infertility may be related to a variety of factors, such as inflammation, obesity, intermittent hypoxia, and sympathetic activation
.
In our previous study, we found that women with non-apneic sleep disorder had an increased risk of infertility
Sympathetic activation,
This study conducted a case-control study (N = 4,078) of female infertile women aged 20 years or older who lived in Taiwan from January 1, 2000 to December 31, 2013, and identified infertile women, A 2:1 matched control group was established with non-infertile women, and multivariate logistic regression analysis was used to further estimate the effect of OSA on female infertility
.
After applying exclusion criteria, 2,400 patients were included and assigned to the study group in the analysis
.
The control group consisted of 4,800 matched women without infertility
In the study population, there were more women aged 26-30 and 31-35 than other age groups (28.
This study used multivariate logistic regression analysis
.
Factors of female infertility are listed in Table 2
This study used multivariate logistic regression analysis
This study is the largest retrospective study to date demonstrating an association between female infertility and obstructive sleep apnea
.
In this province-wide population-based case-control study over 14 years, we found that infertile women had an odds ratio of 2.
This study is the largest retrospective study to date demonstrating an association between female infertility and obstructive sleep apnea
Original source:
Zhu Wei Lim , et al.
Obstructive sleep apnea increases risk of female infertility: A 14-year nationwide population-based study.
Obstructive sleep apnea increases risk of female infertility: A 14-year nationwide population-based study.
Zhu Wei Lim PLoS One.
PLoS One.
Published online 2021 Dec 15.
doi:10.
1371/journal.
pone.
0260842 10.
1371/journal.
pone.
0260842 Leave a message here