Do nutritional supplements really affect the diagnosis?

original title: Do nutritional supplements really affect the diagnosis is not unfamiliar with vitamins, it is necessary to maintain good health, in recent years, the vitamin market scale has maintained high growth, fully demonstrated the growing demand for vitamins in modern people. Modern people like to regularly supplement the vitamins they need to reduce the damage caused by vitamin deficiency and improve physical function. You'll definitely see this often, with friends or family members who get vitamin A, vitamin B, female friends who often take vitamin C or multivitamins to improve their hair and nails, pregnant women's friends who are asked to take Elavi (multivitamins) at a certain time, to help solve the problems caused by vitamin deficiency through nutritional supplements. But if you're in the hospital for some illness, will these vitamin supplements affect your test report? In particular, immune testing programs will affect the judgment of doctors? The answer is yes.which patient specimenshave biotin interference? Biotin, also known as vitamin B7, also known as vitamin H, coenzyme R, etc., is a water-soluble vitamin. Multivitamin supplements are the most common source of oral biotin and are mainly used in adults, children or during pregnancy, as well as in the treatment of people with multiple sclerosis. Patients who take supplements such as Good Storage Tablets, Kinschercon, And Alelevi on a daily basis; people who take high doses of biotin to promote beauty in hair, skin and nails; and patients who need a very high dose of biotin to treat multiple sclerosis (MS) are among those who need special attention. If the patient takes a biotin supplement of 1-30 mg, the residual amount of biotin in the test specimen is 5-100 ng/ml, which will affect the test results. The more biotin content there is orthes, the greater the interference. The half-life of biotin is 8-19 hours, and for patients taking biotin, the testing of the specimen needs to wait 8-19 hours, which is very detrimental to emergency patients.How do you avoid these distractions? First, the clinician will actively ask the patient if he or she is taking a biosupplement to determine if it is biotin. From the patient's point of view, should also be frank to inform the doctor, take their own nutritional supplementtime time, dosage, etc. From the point of view of the inspection department, you can choose the manufacturers and platforms that are not disturbed by biotin, because in immunochemical luminescence testing projects, the primary consideration is the issue of biotin interference. Biomerie VIDAS luminescent immunothness testing platform, using a two-step reaction process, to avoid the combination of free biotin and luminescent substrate, so that the test results more accurate. The French drug regulatory agency ANSM notifies IVD suppliers that the critical value of biotin interference is 1500 ng/ml; Merier VIDAS has been proven to be a testing platform free of biotin interference, as the biotin interference threshold for the VIDAS immunotest project is greater than 2000ng/ml., heart markers should also be detected on platforms that are not interfered with by biotin. Troponin is an important biomarker for diagnosing acute heart attack, sodium peptide is an important biomarker for diagnosing heart failure and acute heart failure, and it is also a very important immune detection project in emergency and chest pain center. If biotin is present in the blood, it can lead to unpredictable "false negative" results in the laboratory's immunotest program tropocalnin indicators. An earlier case report by the FDA showed that a patient taking high levels of biotin had negative tropoprotein results, causing a doctor's misjudgment to cause the patient to die. The selection of a platform free from biotin interference for testing can effectively avoid such medical accidents, through accurate test results, so that patients get the right treatment plan.
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