Diagnosisy: Severe COVID19 patients have signs of brain damage.

, June 20, 2020 /PRNewswire/ --- A study by the University of Gothenburg showed clinical and neurochemical signals of brain damage in some patients hospitalized with coronavirus infection (COVID-19)Even in moderate CASES OF COVID-19, biomarkers associated with brain injury can be found in the bloodsome people infected with the coronavirus SARS-CoV-2 will only develop mild cold-like symptoms, while others are so ill that they need hospital treatmentIn the latter, patients sometimes show signs that the brain is not working properlyThese situations are not common, but they do occur(photo source:in a project at the Sahlgrenska Institute at the University of Gothenburg, researchers took blood samples from 47 patients with mild, moderate and severe COVID-19These samples were analyzed with highly sensitive biomarkers for brain injuryCompare the results with those of the health control groupthe study, published recently in the journal The Journal of The Journal of The Novelic, showed that even in patients with moderate COVID-19, who needed hospital treatment, the levelof son of one of the biomarkers was increasingThis marker, GFAP (neuroglial fibrosis acid protein), is usually found in astrocytes in the brain, but leaks when astrocytes are damaged or over-activatedthe second biomarker found in the study is NfL (neural silk light chain protein), usually found in brain neuronal products, if the brain damage can leak into the bloodIncreased levels of NfL in the blood were found in most patients who required ventilator therapy, and there was a significant correlation between their increase and the severity of the disease"Over time, the increase in NfL levels was greater than what we've seen in previous studies in intensive care units, suggesting that COVID-19 can actually directly cause brain damage,"It's not clear what caused this, and more research is needed," said Henrik Zetterberg, a professor of neurochemistryHe believes that blood tests of biomarkers associated with brain injury can be used to monitor patients with moderate to severe COVID-19 to reduce the risk of brain damage(Bio Valley Bioon.com) source: Clear Signs of brain injury with severe COVID-19
original origin: Nelly Kanberg et al, Neurochemical evidence of astrocytic and neuronal injuryy yn covid-19, .
" DOI: 10.1212/WNL.00000000010111
.