-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Aortic valve stenosis (AS) is a progressive disease that is related to a decrease in the aortic valve orifice and reduced leaflet activity due to calcium accumulation
It is related to the reduction of aortic valve orifice and the reduction of leaflet activity due to calcium accumulation
Methods: From August 2016 to April 2019, we recruited 50 AS patients with type 2 diabetes and 100 non-diabetic and AS patients of similar age and sex as the control group
Results: Compared with the non-diabetic group, the expression of NF-κB, BMP-2, FII and FKA in the diabetic group was increased (ALP≤0.
Table AS, baseline characteristics of patients with or without type 2 diabetes
Table AS, baseline characteristics of patients with or without type 2 diabetesFigure 1 Comparison of the expression of NF-κB and BMP-2 in aortic valve stenosis between AS patients with type 2 diabetes and those without diabetes
Figure 1 Comparison of the expression of NF-κB and BMP-2 in aortic valve stenosis between AS patients with type 2 diabetes and those without diabetes
Figure 2 The correlation between the expression of NF-κB and serum markers of blood glucose control in patients with AS and type 2 diabetes
Figure 2 The correlation between the expression of NF-κB and serum markers of blood glucose control in patients with AS and type 2 diabetes
Figure 3 Comparison of the expression of FII and FXA in aortic valve stenosis between AS patients with type 2 diabetes and those without diabetes
Figure 3 Comparison of the expression of FII and FXA in aortic valve stenosis between AS patients with type 2 diabetes and those without diabetes
Figure 4 The relationship between the valve expression of inflammation, calcification and coagulation factors and the severity of the disease in AS and patients with type 2 diabetes.
Figure 4 The relationship between the valve expression of inflammation, calcification and coagulation factors and the severity of the disease in AS and patients with type 2 diabetes.
Type 2 diabetes can enhance local inflammation and coagulation activity in stenotic valves
Kopytek M, Mazur P, Ząbczyk M, Undas A, Natorska J,D iabetes concomitant to aortic stenosis is associated with increased expression of NF-κB and more pronounced valve calcification.
iabetes concomitant to aortic stenosis is associated with increased expression of NF-κB and more pronounced valve calcification.
Leave a message here
