Current situation, problems and Countermeasures of feed additive industry in China (4.10)

OA show ('918 '); Shen Juncai v3y (Guangxi feed additive research and development center, 530001) reviewed the current situation of China's feed additive industry production, pointed out that there are few varieties, backward technology, lack of innovation and other problems, and put forward key development products and other suggestions The feed additive industry in China started from the early 1980s, with an annual output of more than 250000 tons and an annual output value of 5 billion yuan It has been able to produce about 100 products in 18 categories including vitamins, amino acids, mineral elements and other non nutritive additives More than 80 varieties have been approved for use, of which only more than 40 are domestically produced and standardized, and the rest are foreign products approved for import Compared with developed countries in terms of variety and quantity, imported feed additives are far from meeting the needs of the development of feed industry in China V3y2 The present situation of feed additive production in China v3y2.1 vitamin is an indispensable low molecular organic compound for animals to maintain normal physiological function, with a small amount of vitamin However, due to its special physiological function and remarkable feeding effect, it plays an important role in the growth, development, health maintenance and breeding of animals, so it is essential The largest amount of choline chloride is used, which is also a product with rapid development in China in recent years More than ten production sites have been built around the country, and the production has tended to be large-scale and modernized However, due to the lack of raw material supply, the production has not been carried out at full capacity There are many domestic manufacturers of niacin, nicotinamide, VC, etc., but most of the vitamins produced in China are medical grade, and the quantity is insufficient, and the price is high, so feed vitamins are largely imported V3y2.2 amino acids are mainly methionine and lysine Tianjin chemical plant has imported 10000 t / a methionine production plant from France, and has three sets of lysine production plants with a capacity of more than 3000 t / A: Guangxi lysine plant (5000 t / a), Quanzhou Daquan lysine Co., Ltd (5000 t / a), Sichuan Chemical Plant and Japan Ajinomoto lysine plant (6000 T / a) Nevertheless, the market gap is still large V3y2.3 mineral element and mineral feed additive is a kind of feed additive with the largest amount and the most common use, which accounts for more than 60% of the total consumption of feed additive, among which the phosphate mainly composed of calcium hydrophosphate consumes the largest amount, with a total production capacity of about 160000 tons / year and other trace elements of about 3-4 tons / year V3y2.4 other non nutritive additives, v3y2.4.1 antibiotics and antimicrobial growth promoters have been used as feed additives for more than half a century, with a long time, a wide range, significant effect and most arguments There are mainly macrocyclic lipids, aminoglycosides, polyethers, polypeptides and tetracyclines Synthetic antibiotics are only approved to use olaquindox in China There are many manufacturers and they can be exported V3y2.4.2 in high-density intensive feeding, there are many kinds of parasites with wide distribution and serious harm Once the disease occurs, the infection is fast, resulting in the reduction of production and death, causing serious economic losses, so it is very important to prevent the occurrence of parasitic diseases There are many kinds of anthelmintics, but they are generally toxic They can only be used as drugs for a short time when they are ill, and can not be used as additives in feed for a long time The main products in China are imidazole, avermectin, thioehydropyrimidine, yuemycin a, keqiu powder, Qiuliling, Hainan mycin, salinomycin, Maduramycin ammonium, coccidian powder, dimethylthiamine, Nicarbazine, etc V3y2.4.3 antioxidant and oxygen in the air of mildew inhibitor are the inducement of deterioration and corruption of fat, protein, carbohydrate and vitamin in feed Adding antioxidants to feed can prevent feed from oxidative deterioration The most commonly used is antioxidant quinoline (EMQ) Other varieties include BHA, BHT, PG and VE At present, the market is mainly a compound antioxidant based on anti-oxidation Quine There are many imported products, such as sandoquine, Xianling, anti-oxidation safety, baolexian, and gram oxygen In recent years, some domestic research institutes have carried out research and development to fill this gap, such as Shanghai Changzheng No Under the condition of high temperature and high humidity, the feed is prone to putrefaction and mildew due to the propagation of microorganisms The compound feed produced and stored in rainy season and summer should be added with mildew inhibitor Most of the domestic fungicides are imported propionic acid and propionic acid salts, and other varieties are benzoic acid, fumaric acid, sorbic acid and other products At present, many domestic manufacturers develop and produce sodium diacetate as a mold inhibitor V3y3 The main problems and gaps in the development of feed additives, resulting in the lack of product varieties and quantity, will be an important factor restricting the development of compound feed production in China in the medium and long term, and also one of the main problems facing the development of feed industry Although China's feed additive industry has developed rapidly in recent years, compared with developed countries, it is still at a relatively backward level, mainly reflected in: v3y 3.1 has fewer varieties and a small number of about 100 varieties approved for use in China, while there are about 250 in the United States, about 120 in Japan, and about 260-270 in the European community In addition, the total output is low, and many varieties, including raw materials, are imported V3y3.2 lack of funds and backward technology is based on the important role of feed additives in feed industry Developed countries regard it as a high-tech project and attach great importance to its development China's economic and technological strength is relatively backward compared with developed countries High-tech and high value-added technology intensive products, such as amino acids, vitamins, antibiotics, etc., are still in the situation of high cost and dependence on imports Although there are more than one thousand feed additive manufacturers in China, they are small in scale, most of them are produced repeatedly, with serious segmentation and nonstandard industry management V3y 3.3 is lack of innovation and Imitation Based varieties currently produced in China, mainly imitation based, with little innovation Bioengineering technology products and drug additives have good development prospects due to their low pollution, non-toxic and broad-spectrum characteristics We should explore creative research fields in this area V3y4 Development proposal recently, the State Council issued the regulations on the administration of feed and feed additives, indicating that the Chinese government attaches great importance to the development of feed industry In the future, we should actively develop new technologies, increase investment, attract foreign investment, create a good investment environment, expand technical exchange and cooperation with foreign countries, introduce advanced equipment, strengthen technological transformation of existing products, expand production scale, improve product quality and reduce production costs Specifically, the following aspects deserve our attention V3y4.1 the development of feed drug additives should develop antibiotics and insect repellent health agents that are harmless to human, livestock and environment, are not easy to produce drug resistance, and have little or no residues in animal tissues Microbial additives and Chinese herbal additives are non-toxic, no side effects, no residues, and have certain development potential V3y4.2 vigorously develop the amino acid industry because the annual production capacity of domestic methionine and lysine is less than 20000 tons, the demand is about 100000 tons, and the gap is very large Therefore, vigorously develop the amino acid industry, further introduce the production equipment of 30000-50000 tons / year methionine, expand the production of lysine, reduce the cost, and improve the acid production rate and extraction rate The main problem of mineral elements in v3y 4.3 is the variety problem There are more than 30 ~ 40 varieties approved in foreign countries, but only 10 in China Copper, iron, zinc and manganese approved for use in China are only sulfates, while there are oxides, chlorides and carbonates in foreign countries It is worth noting that more and more salts or amino acid salts of organic acids, such as citrate, lactate, niacin and amino acid chelates, have been used in foreign countries In addition to supplement major or trace elements, they can also provide nutritional ingredients Therefore, it is worth actively developing and researching to expand the variety of mineral element additives, so that mineral element products will develop in a diversified direction In addition, the production of mineral element additives must be subject to strict quality monitoring Many manufacturers produce or use industrial grade products to replace feed grade products Although there is no problem in a short period of time, but over time, livestock and poultry products have a high residual amount of heavy metals, which ultimately harms people's health This is a problem that cannot be ignored The development direction of v3y4.4 non nutritive additives is to develop antioxidant varieties mainly composed of ethoxyquine, which has low price and good effect, and is most commonly used in feed industry abroad In practical application, it is usually based on ethoxyquine, which uses a variety of antioxidants to form a synergistic composite antioxidant Some key equipment for propionic acid production can be imported to match domestic technology to form production capacity and change the situation of completely relying on imports It should be regarded as a great event in feed industry to set up a large-scale plant for propionic acid production by carbonyl synthesis In addition, the development and application of calcium formate and sodium diacetate in feedstuff, especially in silage, are also noteworthy Non protein nitrogen additive is an important way to supplement protein, the main variety is urea In order to prevent poisoning caused by improper urea feeding, safe non protein nitrogen additive should be developed and applied, but the key is its price If it is much higher than urea, it is not easy to pass the economic test Urea phosphate has been used in dairy production in Inner Mongolia and Guangxi We should develop bioengineering technology, use advanced technology such as gene recombination, cell fusion and large-scale cell culture to cultivate new strains and improve feed efficiency References: 1 Hua Hao China Chemical Market Express 1999 (23): 28-30 2 Yu Hong et al Hunan chemical industry 1997 (3): 21-22 3 Wang Gang et al Feed research 1999 (1): 28-29 4 Li Meitong Et al Feed additive Beijing University Press with English title and Abstract: the present situation, problems, and Countermeasures of the Development of Feed Additives Industry in our country Shen Juncai Guangxi Centre of Research and Development on Feed Additives Abstract: The present situation of the development of feed additives industry in our country is discussed in this paper The problems are less of variety, backword in technology and lack of innovation Finally some suggestions such as the major products that should be developed are put forword Keywords: feed additives, the present situation of the development, Counter measures Author information: Shen Juncai mailing address: Guangxi Chemical Research Institute, No 7, Erli, Wangzhou Road, Nanning City, Guangxi Province zip code: 530001 Tel: 0771-3316096-2211 e-mail: gxrici@public.nn.gx.cn China feed industry information network v3y (author:)