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Social contact is the primary wayof social behavior.
1
Neurons in the PIN region regulate social hair management behavior
The researchers found that through chemical genetics, the chronic activation of female rat PIN regional neurons promotes social hair management behavior (peer hair management behavior), and social hair management behavior
after inhibiting neuronal activity in this region.
Figure 1: Neurons in the PIN region regulate social hair management behavior
2
The PIN brain region is projected downstream to the brain area
After the anterograde tracer virus is injected into the female rat PIN, it can be projected to multiple brain regionssuch as the marginal subcortical layer (ILC), lateral septal nucleus (LS), MPOA, end-striated ventral nucleus, hypothalamic paraventricular nucleus (PVN), medial amygdala (MeA), dorsoposterior hypothalamic nucleus (DMH), central gray matter (PAG) around the midbrain aqueduct, and parabrachial lateral nucleus (LPB).
Figure 2: PIN brain regions are projected onto multiple downstream brain regions
3
PIL ➟MPOA peptide energy loop
Social behavior in social settings activates MPOA region inhibitory neurons close to PTH2-positive fibers.
Figure 3: PIL ➟MPOA peptide energy loop regulates hair management behavior
summary
In this paper, through viral tracing and chemical genetics, we revealed the peptide-capable neural circuits that regulate the social hair management behavior of female rats: posterior medial nuclei expressing PTH2-positive neurons projected onto the medial preoptic region inhibitory neurons
.
【References】
1.
https://doi.
The images in the article are from references
