Cure 90% of severe illness in 5 days?

Since the outbreak of the epidemic, new crown "variant viruses" have appeared in many countries, from Alpha to Delta, all of which have come aggressively

In the past two months, the mutant strain has become one of the main epidemic strains of the new crown virus in many South American countries such as Peru, Chile, Argentina, and Colombia , and has now spread to more than 30 countries

In the face of the crazy mutation of the new coronavirus, breakthrough infection seems to be expected

The effectiveness of the drug under development exceeds 90%

With the efforts of scientific researchers around the world to race against time, a number of phased scientific research results have been produced at home and abroad

Professor Israel Yiqiluofu hospital Nadir Albert (Nadir Arber) research team also found a magic pill "EXO-CD24" , which is a fixed small on the human cell membrane protein with cytokine The function of the storm

The drug was approved for the first clinical trial by the Israeli Ministry of Health in September last year.

At present, the team has begun looking for 155 severely ill patients with new coronary disease to start the final phase of clinical trials, which will be completed before the end of the year

"New use of old drugs" can reduce more than 70% of new crown infections

It is worth noting that since it often takes about 10 years for a new drug to be developed in the laboratory to market, but the reality cannot tolerate such a long wait, so scientists have turned their attention to " new use of old drugs

Recently, the University of Birmingham and the University of Kiel in the joint research team " Frontiers in Pharmacology " magazine published by SARS-CoV-2 in Cell Culture Models articles, studies indicate that an article entitled The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection lipid-lowering The drug "fenofibrate" and its active form " fenofibric acid" can significantly reduce SARS-CoV-2 infection in human cells, and the effectiveness can reach 70% !

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Fenofibrate is a blood lipid regulating drug.

In this latest study, researchers analyzed the active metabolite "fenofibric acid" of fenofibrate based on enzyme-linked immunosorbent assay (ELISA) and whole cell fusion test.

The effect of fenofibrate on the combination of RBD and ACE2

In order to further evaluate the potential therapeutic effect of fenofibrate, researchers analyzed the inhibitory effect of fenofibric acid on the proliferation of two different SARS-CoV-2 isolates in Vero cells

Fibrate inhibits SARS-COV-2 infection of Vero cells

Currently, the team is calling for clinical trials, hoping to test the drug in hospitalized COVID-19 patients

Although the study is only an in vitro test, it still has guiding significance.

Reference materials:

[1]https://mp.

[5]https://mp.
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