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    Home > Medical News > Latest Medical News > CSPC Claudin 18.2 targets ADC to initiate clinical co-targeted monoclonal antibody up to US$640 million to go overseas

    CSPC Claudin 18.2 targets ADC to initiate clinical co-targeted monoclonal antibody up to US$640 million to go overseas

    • Last Update: 2021-08-27
    • Source: Internet
    • Author: User
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    On August 17, the Insight database showed that the SYSA1801 injection, a class 1 new drug of CSPC Jushi Biologics, started clinical trials for CLDN18.


    On the same day, CSPC announced that its subsidiary NovaRock has reached a cooperation with Flame Biosciences, Inc.


    In this transaction, CSPC received a down payment of US$7.


    From the Insight database

    Claudin 18.


    Claudin 18.


    According to the Insight database, there are currently 19 biological drugs targeting Claudin 18.


    Claudin 18.


    Gastric cancer is a cancer with a higher incidence in Asian countries such as China, Japan and South Korea


    CSPC's Claudin 18.


    CSPC's Claudin 18.


    In November last year, SYSA1801 was approved as an orphan drug by the FDA for gastric cancer and gastroesophageal junction cancer


    NBL-015 is a fully human anti-Claudin 18.


    At present, NBL-015 has been approved by the US FDA as an orphan drug for the treatment of pancreatic cancer and gastric cancer (including cancer of the esophagus and gastric junction), and its IND application has also been approved by the US FDA in May 2021


    NovaTE is a novel tumor antigen and CD-137 dual antibody technology platform, which aims to selectively activate T cells with antigen experience in the tumor microenvironment


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