Cruciferae helps prevent and treat pancreatic cancer

"Dimeric indole, a nutrient extracted from cruciferous vegetables, can promote the differentiation of pancreatic cancer cells and play a unique anti-cancer activity." Recently, a scientific research project jointly completed by Li Zhiwei, associate professor of the Department of digestive oncology, the Third Affiliated Hospital of Harbin Medical University, and experts from MD Anderson Cancer Center in the United States has provided an important theoretical basis for people to use the effective ingredients of natural plants to prevent and treat pancreatic cancer Cruciferous vegetables mainly include cabbage, cabbage, mustard and radish Epidemiological studies show that cruciferous vegetables can reduce the risk of some cancers, such as lung cancer, colon cancer, breast cancer and so on Among them, broccoli (green cauliflower), radish, cabbage and cabbage have the most outstanding anti-cancer effect The reason why cruciferous vegetables can prevent cancer and fight cancer is that they contain phytochemicals, such as isothiocyanate and indole, but the exact mechanism of which is still unknown in the scientific community In January 2011, Dr Li Zhiwei went to the digestive department Research Office of MD Anderson Cancer Center in Houston to do postdoctoral research In the world's leading cancer diagnosis and treatment center, he and his colleagues cooperated to mix the natural chemical component of Cruciferae, dimeric indole, with pancreatic cancer cells, and found that the former can significantly inhibit the growth of the latter, which is dose-dependent; At the same time, it can promote the differentiation of pancreatic cancer from high-grade to low-grade cells, regulate the differentiation and the expression of stem cell molecular markers In their study, they also found that KLF4, a substance called KLF4, plays a "switching" role in the anti-tumor growth of dimeric indole and the promotion of cancer cell differentiation The results of this study lock the key target of the dimer indole anti-cancer channel, and provide a scientific basis for the prevention and treatment of pancreatic cancer At present, pancreatic cancer is regarded as the king of cancer Once the patient enters the middle and late stage, the survival time is very short and the prognosis is extremely dangerous The results of this study suggest that, as the extract of Cruciferae, dimeric indole can not only inhibit the occurrence of tumor and promote the differentiation of cancer cells to normal cells, but also further clarify that this nutrient can control the expression of related genes, and thus prevent the relentless "nibbling" of pancreatic cancer on life If people can effectively and reasonably use these natural biological components, it is expected to reduce the incidence of pancreatic cancer If we can develop relevant regulatory drugs for key targets, it will bring a new dawn for the treatment of pancreatic cancer.