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    Home > Biochemistry News > Biotechnology News > Cracks the mechanism by which skin cancer metastasizes to the brain, where spread can be suppressed by 80%

    Cracks the mechanism by which skin cancer metastasizes to the brain, where spread can be suppressed by 80%

    • Last Update: 2022-10-02
    • Source: Internet
    • Author: User
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    Researchers at Tel Aviv University have for the first time cracked a mechanism that enables skin cancer to metastasize to the brain and have successfully delayed the spread of the disease by 60 to 80 percent


    Professor Satchi-Fainaro explains: "In the advanced stages, 90% of patients with melanoma (skin cancer) develop brain metastases


    Researchers from Tel Aviv University have found that in brain-metastatic melanoma patients, cancer cells "recruit" a type of cell called astrocytes, which are found in the spinal cord and brain and are responsible for homeostasis, or maintaining a stable state


    Professor Satchi-Fainaro said: "Astrocytes are the first cells to correct a condition in the event of a stroke or trauma, with cancer cells interacting with astrocytes to exchange molecules and corrode them


    To test their hypothesis, Professor Satchi-Fainaro and her team sought to inhibit the expression


    Professor Satchi-Fainaro said: "These treatments have been successful in delaying the entry of cancer cells into the brain and subsequent spread


    The study was conducted in collaboration with other scientists and doctors from Tel Aviv University, including Professor Adi Barzel, Dr.


    The study was funded


    Sabina Pozzi, Anna Scomparin, Dikla Ben-Shushan, Eilam Yeini, Paula Ofek, Alessio D.


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