Counting: Shortest time! Chinese scholars have surpassed 100 CNS achievements in the field of life sciences; Gao Fu/Rao Zi and/Qinchuan have more than 4 articles; and Shanghai University of Science and Technology and Shandong Agricultural University have performed well.

As !---- of July 27, 2020, Chinese scholars published 102 life science research projects in Cell, Nature and Science, with nearly half (43) of new crown pneumonia.iNature system summarizes these findings: by magazine: Cell published 30 articles, Nature published 45 articles, Science published 27 articles; 11, Shanghai University of Science and Technology, 8, China Academy of Medical Sciences 7, Peking University 6, Hong Kong University 6;1. As of July 27, 2020, Chinese scholars have published 102 articles on CNS, the specific list of units is as follows: 2. The list of articles is as follows (the articles related to the new crown field in red font): 3. All articles parsed list: 1 2020 On January 1, Li Yunkai of China Agricultural University and Liu Jianguo of Michigan State University co-published a research paper entitled "Assessing progress progress progress es s sustainable development over space and time" online at Nature, which developed and tested systemmethods to quantify China's progress in achieving 17 SDGs at the national and subnational levels.in summary, the study provides time sustainability assessments for all 17 sDGs at the national and subnational levels.therefore, the method outlined in this paper is of great value to China's monitoring work.approach could also provide a basis for an analysis of space-time models of progress on sustainable development goals in other countries, as well as at the local and global levels.finally, this article was selected as the cover of the latest issue of Nature, and on January 15, 2020, Tongji University's Gobao And Shanghai University of Science and Technology Rao Zi and The Common Seincoma published a research paper entitled "Host-mediated ubiquitination of a mycobc protein spent", published on Nature online. The study found that the host E3 unoquilateenzyme ANAPC2 (the core sub-sub-subtype of late-promoting complex/cyclins) interacted with mycobacterium protein Rv0222, and promoted the attachment of the unonine chain to Rv02222, thereby inhibiting the expression of inflammatory cytokines.in general, the study identified a previously unknown mechanism used by mycobacterium tuberculosis to suppress host immunity and provided insights related to the development of effective immunomodulators for mycobacterium tuberculosis.3, 2020, Wang Xiaoqun of the Institute of Biophysics of the Chinese Academy of Sciences and Wu Wei of Beijing Normal University published a research paper entitled "Decoding the development of the development of the human hippocampus" online in Nature, using single-cell RNA sequencing and sequencing (ATAC-seq) analysis to determine the color that transposonase is close to, to illustrate the type of human hippocampus cells in development.in general, these data provide a blueprint for understanding the development of human seahorses and tools for investigating related diseases., January 16, 2020, He Chuan, University of Chicago, Beijing Genomics Institute of the Chinese Academy of Sciences Han Kea and Tongji University Gao Yawei joint newsletter in Science online entitled "N6-methyladenosine of chromosome-type-regulatoryed RNA" Regulates chromatin state and ion" research paper, which showed that knocking out m6A catalytic protein Mettl3 or nuclear-identified protein Ythdc1 in mouse embryonic stem cells increased the accessibility of chromatin and activated transcription in m6A-dependent manners.the study found that METTL3 deposited m6A modifications on chromosomal-related regulated RNA (carRNA), including promoter-related RNA, enhancer RNA and duplicate RNA.in general, the results show that m6A on carRNA can globally regulate chromatic status and transcription.5. The chromatin remodeling protein SWI/SNF family of mammals, BAF and PBAF regulate the structure and transcription of chromatin, whose mutations are associated with cancer.January 30, 2020, Xu Yanhui's team at Fudan University published an online paper entitled "Structure nucle of osome-bound human BAF complex", which obtained a 3.7-resolution nuclear small body binding human BAF's frozen EM structure, revealing that the nucleosome is sandwiched between the base and ATPase module, which is connected by the armibokine-related protein (ARP) module.the study provides structural insight into the identification of sub-base tissues and nuclear small bodies of human BAF complexes.selectively targeting CB2 drugs is expected to treat neurodegenerative diseases, inflammation and pain while avoiding CB1-mediated psychotic side effects. little is known about the mechanisms of CB2 activation and signal transduction, but it is critical to drug design. January 30, 2020, Xu Huaqiang of the Shanghai Institute of Medicine of the Chinese Academy of Sciences and others published an online research paper entitled "Cryo-EM Structure of Human Cannabinoid CB2-Giing Signal Complex" published online in Cell, which reported the frozen EM structure of the human CB2-Gi signal complex bound to the agonisant WIN 55,212-2. 3D structure reveals the combination pattern of WIN 55,212-2 and the structural decision clusters used to distinguish CB2 agonists from antagonists. further structural analysis of with computational docking results reveals differences in receptor activation, ligand recognition and Gi coupling between CB2 and CB1. these findings are expected to lead to the discovery of drugs targeting the cannabinoid system. , January 30, 2020, Shanghai University of Science and Technology Liu Zhijie and Hua Sweet Co-newsletter published a research paper on Cell online entitled "Activate and Signaling Mechanism Revealed by Cannabin Receptor-Gi Complex Structures", which opened up the mystery of cannabinoid receptorS CB1 and CB2, respectively, antagonistic, intermediate and activated states, and took another solid step forward in understanding the cannabinoid system. , the study also revealed the molecular mechanism of CB2 receptor acquisition of highly selective ligands, providing a more accurate molecular model and theoretical basis for the design of new immunology drugs for CB2. , January 30, 2020, Beijing University Tang Fuhui and Liu Guanghui, Qu Jing, Juan Carlos Izpisua Belmonte, Of the Institute of Zoology of the Chinese Academy of Sciences, published "Single Cell Cellomic Atlas" online Of The Primate Ovarian Aging" research paper (cover article), the first high-precision single-cell transcription sequencing technology to map the single-cell aging of the ovaries of crab monkeys, and the use of human ovarian cell research system, found that the decline in the antioxidant capacity associated with aging is one of the main characteristics of primate ovary aging. 's research paper entitled "The water water lily lily and the evolution of the evolution" by Zhang Liangsheng of Fujian Agricultural and Forestry University. the study obtained a high-quality genome of blue star water lily, and demonstrated the evolutionary characteristics and characteristics of early quilt plants through its genome and transcription group results, while analyzing the flower organ development and flower-scented color regulation genes of water lily, which is of great reference value to the application of horticultural plant molecular breeding. on February 3, 2020, Zhang Yongzhen's team at Fudan University published an online research paper entitled "A new coronavirusvirused with human respiratory disease in China" in Nature, which reported on a patient working in a seafood market who was admitted to Wuhan City Central Hospital on 26 December 2019 and was admitted to Wuhan City Central Hospital with severe respiratory syndrome, including fever, dizziness and cough. genome RNA sequencing of bronchial alveobubble irrigation samples, a new type of RNA coronavirus, known here as the WH-Human-1 coronavirus (also known later as 2019-CoV). systematic evolutionary analysis of the complete viral genome (29,903 nucleotides) showed that the virus was most similar to a group of SARS-like coronaviruses (89.1% nucleotide similarity). the high similarity and predicted protein structure of amino acid sequences between the 2019-nCoV and SARS-CoV RBD domains, 2019-nCoV may be effective in using human ACE2 as a cell entry receptor, potentially promoting human-to-human transmission. 2019-nCoV is most closely associated with bat coronaviruses, and even in nsp7 and E proteins show edire of 100% amino acid similarity to Bat-SL-CoVZC45. therefore, these data suggest that bats may be hosts of 2019-nCoV. however, since a variety of animals were on the market for sale when the disease was first reported, more work was needed to determine the natural and intermediate hosts of 2019-nCoV. , February 3, 2020, the Wuhan Virus Institute of the Chinese Academy of Sciences, Shi Zhengli team published online in Nature entitled "A pneumonia outbreak with a new coronavirus of the probable bat origin", which believes that bats are the most likely to carry 2019-nCoV virus wildlife. , February 6, 2020, Xiao Junyu's team at Peking University published a research paper entitled "Structural insights into immunoglobulin M" in Science, which reported on the structure of frozen electron microscopes in the Human IgM Fc area with J-chain and pIgR extraterrestrial complexes. the IgM-Fc pentapolymer is asymmetrically formed, similar to a hexagon with a missing triangle. IgM-Fc's tail is packaged as amyloid to stabilize the pentapolymer. The J-chain seals the tail-wing assembly and bridges the interaction between IgM-Fc and pIgR, which undergoes a large conformational change to engage with the IgM-J complex. these results provide a structural basis for IgM's functionality. , February 6, 2020, at Science, Wang Lang and Gu Yan of Zhejiang University published a research paper entitled "Microglia for mediate via-dependent synapsateddit" in Science, which reported that small glial cells in healthy adult mice hippocampuses devoured synaptic components. reduction of small glial cells or inhibition of small glial cells' phagocytosis prevents the separation of forgotten and "imprinted" cells. by introducing CD55 inhibitory complements, especially in engram cells, the study further demonstrates that small glial cells regulate oblivion in complement and active dependence. in addition, small glial cells are involved in neural occurrence associated with neural development unrelated to memory degradation. together, the results suggest that synaptic elimination of small glial cells dependent on complements is a potential mechanism for forgetting remote memories. , February 6, 2020, Fu Xiangdong of the Institute of Genetic Development of the Chinese Academy of Sciences and Nicholas P. Harberd of the University of Oxford co-published a research paper entitled "Enhanced sustainable green revolution field via dven-responsive modulation in rice" in Science, which found that nitrogen state affects chromatin in rice through the modification of histones, in which the transgenic factor NGR2 is collected. some of these genes, for example, as nitrogen levels increase, plants produce more divisions. NGR5 is regulated by protease destruction and mediates hormone signaling. increase in NGR5 levels can drive rice distribution and yield increase, without adding nitrogen-rich fertilizers. 15 2020.