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Combination therapy for diabetes improves the effectiveness of insulin replacement therapy in mice

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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A team of researchers at Nagoya University in Japan has discovered a new way to treat type 1 diabetes by using leptin, a hormone secreted by fat cells

It is important

Scientists who study rodents have found that giving leptin to animal models of insulin-dependent diabetes without the use of insulin normalizes

The research team, consisting of Ryoichi Banno, an associate professor at the Center for Health, Physical Fitness, and Exercise Studies at Nagoya University, in collaboration with Professor Hiroshi Arima of the Department of Diabetes and Endocrinology, found that the limited potency of leptin can be improved

The protein tyrosine phosphatase 1B (PTP1B) is an enzyme

The group intends to conduct further research to evaluate future clinical applications

The research was supported by the Young Scientist Grant Fund of the Japan Association for the Promotion of Science (2618K16225) and the IDDM Network of Japan

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