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Recently, Coba Bio announced the initiation of a phase I clinical trial of its self-developed monoclonal antibody drug SPX-101 in the United States, mainly to explore the safety and efficacy of SPX-101 in the treatment of patients with advanced pancreatic cancer, gastric cancer, bile duct cancer, and ovarian cancer.
SPX-101 is a humanized monoclonal antibody specific for claudin 18 splice variant 2 (CLDN18.
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