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8, 2020 /--- In a recent study, Dr. Nicolas Bazan, Professor Boyd, and Professor of Neurosurgery, Ludmila Belayev, from LSU School of Health, revealed key basic mechanisms for brain cell communication during stroke.
they found that DHA not only protects and promotes the survival of neuron cells, but also helps maintain their integrity and stability.
findings provide potential new clinical targets for the treatment of ischemic stroke and other cardiovascular diseases.
their findings were published in the journal CNS Neuroscience and Therapeutics.
(Photo: www.pixabay.com) The synchronous characteristics of brain cells talking to each other regulate nerve inflammation and the immune system.
the process activates the brain during attacks of stroke, Alzheimer's, Parkinson's and other diseases.
researchers found that in stroke models, DHA affected the levels of two proteins that were essential for communication between brain cells, namely the central brain astrocyte cell-based neurotrophic factor (MANF) and the trigger recepctor expressed on myelin cell 2 (TREM2).
they found that treatment with DHA reduced the size of damaged brain regions, initiated repair mechanisms, and greatly improved nerve and behavioral recovery.
these findings provide important advances in the broad correlation between neuron cell survival, brain function, especially stroke and neurodegenerative diseases.
DHA consists of omega-3 ultra-long chain polysaturated fatty acids (VLC-PUFAs, n-3).
it is widely found in fatty cold-water fish such as salmon.
other benefits, DHA is essential for normal brain function in adults and for the growth and development of the baby's brain.
Bazan said: "Our findings go a long way toward understanding the cell interactions between neurons, aston glial cells and small glial cells to maintain synth circuits and restore pathological disorders.
" these findings have contributed to an understanding of how to maintain the complexity and elasticity of the human brain.
these new molecules are involved in transmitting information to the entire synth tissue to ensure that it flows accurately through the neuron circuit.
(bioon.com) Source: Research unlocks key mechanism in the communications between brain cells during stroke Original source: Belayev, L., et al. (2020) DHA modulates MANF and TREM2 abundance, enhances neurogenesis, reduces infarct size, and snooker. CNS Neuroscience and Therapeutics. doi.org/10.1111/cns.13444.