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    Home > Active Ingredient News > Antitumor Therapy > Clinical Lung Cancer: Delayed dosing of immune checkpoint inhibitors (ICIs) under the influence of the new crown epidemic does not affect the efficacy of NSCLC patients

    Clinical Lung Cancer: Delayed dosing of immune checkpoint inhibitors (ICIs) under the influence of the new crown epidemic does not affect the efficacy of NSCLC patients

    • Last Update: 2022-02-18
    • Source: Internet
    • Author: User
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    Recently, Clinical Lung Cancer published a retrospective study to evaluate the safety and efficacy of delayed administration (EI) of immune checkpoint inhibitor (ICI) in patients with non-small cell lung cancer under the influence of the new coronary pneumonia epidemic.


    Recently, Clinical Lung Cancer published a retrospective study to evaluate the safety and efficacy of delayed administration (EI) of immune checkpoint inhibitor (ICI) in patients with non-small cell lung cancer under the influence of the new coronary pneumonia epidemic.


    In this retrospective analysis, patients receiving ICI monotherapy or consolidation therapy or adjuvant ICI therapy were evaluated


    In this retrospective analysis, patients receiving ICI monotherapy or consolidation therapy or adjuvant ICI therapy were evaluated


    The study included 205 patients, of whom 117 received the EI dose and 88 received the SD dose




    Among patients receiving pembrolizumab monotherapy, with a median follow-up of 93.


    Among patients receiving durvalumab, with a median follow-up of 54.


    Among patients receiving durvalumab, with a median follow-up of 54.


    Among patients receiving nivolumab, with a median follow-up of 98.


    Among patients receiving nivolumab, with a median follow-up of 98.


    In conclusion, delayed administration (EI) of ICIs did not result in an increase in clinically relevant toxicity, leading to dose reduction and/or treatment discontinuation


    In conclusion, delayed administration (EI) of ICIs did not result in an increase in clinically relevant toxicity, leading to dose reduction and/or treatment discontinuation


    Original source:

    Please cite this article as: LBM Hijmering-Kappelle et al, Safety and Efficacy of Extended Interval Dosing for Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer During the COVID-19 PandemicAU: Please provide the academic degrees of corresponding author.


    Please cite this article as: LBM Hijmering-Kappelle et al, Safety and Efficacy of Extended Interval Dosing for Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer During the COVID-19 PandemicAU: Please provide the academic degrees of corresponding author.
    , Clinical Lung Cancer, https://doi org/10 1016/j cllc 2021 12 005 COVID-19

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