Clin Rheumatol: Prognostic factors for early recurrence of gout in patients who started uric acid reduction treatment during acute gout attacks

Reducing serum urate levels below the crystal formation threshold with urate-reducing therapy (ULT) is associated with a reduced risk of recurrence of gout attacksHowever, gout patients with ULT often still have repeated episodes of goutThe purpose of this study was to explore the prognostic factors associated with the recurrence of gout attacks in patients who started ULT during acute gout episodes during the first 3 monthsafter-the-fact analysis of experimental data for patients with acute gout randomly classified as standard gout or anakinra treatment, including baseline demographics, laboratory, clinical and patient reporting variables, and follow-up data for 3 monthsThe outbreak of gout recursOnly patients who start WITH ULT from the baseline are includedUsing the selection of variables based on clinical correlation, a single variable and multiple binary logistic regression analysis were carried out to check the predictors of gout recurrencestudy included 75 patients, 36 (48%) of whom developed gout attacks within three months of the baselineMultiregression analysis showed a lack ofprevention at CRP levels of 30 mg / L (OR 9.47) and starting ULT (OR 11.56)were independently associated with recurrence of gout attacksSingle-variable regression analysis found similar results, the results show that in patients who startED ULT during an acute gout attack, the lack of prevention at CRP levels of 30 mg / L and the onset of ULT was a prognostic factor for the recurrence of early gout attacks