 Home > Active Ingredient News > Antitumor Therapy > Clin Lymphoma Myeloma Leuk: CAR-T therapy can be used to treat patients with relapsed/refractory B-cell acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation

Clin Lymphoma Myeloma Leuk: CAR-T therapy can be used to treat patients with relapsed/refractory B-cell acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation

 Last Update: 2021-05-20
 Source: Internet
 Author: User

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Currently, in patients with acute lymphoblastic leukemia who relapse after allogeneic hematopoietic stem cell transplantation (Allo-HSCT), there is a lack of safe and effective rescue therapy.

stem cell

From September 2017 to October 2019, the study included 11 patients with B-cell acute lymphoblastic leukemia who relapsed after Allo-HSCT treatment.

The results showed that 8 patients (72.

In summary, the results of this prospective study show that allogeneic donor-derived anti-CD19 CAR T cell therapy is a safe and effective rescue plan, suitable for relapsed/refractory B-cell acute lymphocytes after allogeneic hematopoietic stem cell transplantation Patients with leukemia.

Original source:

Jingsheng Hua, et al.

ncbi.
nlm.
nih.
gov/32507386/" target="_blank" rel="noopener">Allogeneic Donor-Derived Anti-CD19 CAR T Cell Is a Promising Therapy for Relapsed / Refractory B-ALL After Allogeneic Hematopoietic Stem-Cell Transplantation

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