Clin Exp Rheumatol: Midax spinal arthritis patients with cervical artery ultrasound reclassified as hyper-high-risk cardiovascular risk

Subclinical atherossclerosis, defined as the presence of cervical plaques, is more common in patients with midashaft spinal arthritis (axSpA) than in healthy individualsThe study was designed to determine whether axSpA patients were classified as hyperrisk cardiovascular risk more than the control group after an ultrasound of the carotid artery and whether it was related to disease characteristicsstudy included 343 axSpA patients and 177 controls diagnosed under asAS standardsAssessed disease characteristics and systemic coronary risk assessment (SCORE) for patients and controlsThe presence of plaques and mid-layer thickness of the lining (cIMT) is determined by cervical arterial ultrasoundMulti-factor regression analysis was performed to determine differences in the incidence of reclassification between patients and controls, as well as factors associated with axSpA reclassificationwas more common than control group, axSpA patients with cervical artery plaques (36% vs25%, p.010) and cIMT thickening (0.641?0.121 vs.0.602.0.115mm, p.001)Patients with axSpA were more likely to be reclassified to high-risk categories (34% vs.25%, p.037)After multi-factor analysis, age (axSpA patient beta factor 2.74 (95%CI 1.34-5.62) vsbeta coefficient 0.63 (95% CI 0.40-0.99), p interaction s 0.001) and serum LDL-cholesterol (beta coefficient 1.03 s.95%) vs1.02-1.04The beta coefficient of 1.00 (0.99-1.01) and p interaction of 0.029 had a greater effect on the reclassification of the control groupAlthough axSpA reclassification was associated with higher ASDAS-CRP, BASFI and BASMI scores, these correlations no longer existed after adjusting for cardiovascular risk factorspatients with axSpA after cervical arterial ultrasound were more likely to be reclassified to the ultra-high risk category than in the control groupTraditional cardiovascular risk factors had different effects on reclassification of patients and control groups