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    Home > Active Ingredient News > Immunology News > Clin Exp Rheumatol: Effects of coronary symptoms in patients with arteritis on long-term prognosis

    Clin Exp Rheumatol: Effects of coronary symptoms in patients with arteritis on long-term prognosis

    • Last Update: 2020-06-05
    • Source: Internet
    • Author: User
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    The purpose of this study was to determine the predictors of coronary damage in patients with major arteritis (TAK) and to determine the effect of coronary retiredness on long-term outcomesthe retrospective cohort study conducted angiography or CT angiography coronaveosion assessment of PATIENTS with TAK at a tertiary center from 1990 to 2018The risk factors of coronary retired and the predictable factors of total survival rate, no cardiovascular event survival rate and non-recurrence survival rate were analyzedmedian follow-up time of 4.3 years (IQR 2.8-7.1)Of the 130 continuous TAK patients, 71 (54.6%) had coronary retirednessThe multi-factor analysis showed that age (OR: 1.537, 95% CI: 1.176-2.009, p-0.002) and V-type angiography classification (OR:3.449, 95% CI: 1600-7.437, p-0.002) were independent reformers of the coronary pulseCoronary retired (HR: 8.358, 95% CI: 1.887-37.033, p-0.015), left ventricular constriction dysfunction (HR: 3.889, 95% CI: 1.467-10.311, p-0.006) and aortic valve reflux (HR: 3.373, p.015), 95%CI: 1.209 -9.408, p-0.020) is an independent predictor of overall survivalIn addition, coronary and baseline active diseases and major cardiovascular events (HR: 10.333, 95% CI: 2.326-45.906, p-0.017; HR: 7.084, 95%CI: 1.677-29.914, p-0.) 008) and recurrence increase is independently related (HR: 5.186, 95% CI: 2.381-11.295, p 0.001; HR: 5.694, 95% CI: 2.022-16.031, p-0.001, p.001, respectively)No immunosuppressive therapy was independently associated with increased cardiovascular events (HR: 2.560, 95% CI: 1.15-1.550, p-0.002)coronary strain is an important predictor of long-term poor prognosis in TAK patientsThe age-old and V-type angiography classification helps to identify PATIENTs with TAK who have coronary affected
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