 Home > Active Ingredient News > Antitumor Therapy > Clin Cancer Res: Treatment of non-Hodgkin's lymphoma with anti-CD79B antibody drug conjugate DCDS0780A

Clin Cancer Res: Treatment of non-Hodgkin's lymphoma with anti-CD79B antibody drug conjugate DCDS0780A

 Last Update: 2022-01-07
 Source: Internet
 Author: User

Tags

fluticasone drug class

pilocarpine side effects

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Using antibody-drug conjugates (ADC) to target CD79B is an effective treatment strategy for B-cell non-Hodgkin's lymphoma (B-NHL)

This is a phase 1 clinical trial that recruited 60 histologically confirmed patients with B-cell non-Hodgkin's lymphoma who had relapsed after previous (≥1 line) treatment or had failed treatment: 41 (68%) Diffuse large B-cell lymphoma (DLBCL)

Research design

The results of the study showed that 54 (90%) patients experienced side effects related to the study drug , the most common of which were blurred vision, fatigue, corneal deposition, neutropenia, nausea, and peripheral neuropathy

54 (90%) patients experienced side effects related to the study drug

Treatment response

The remission rate of all patients (n=60) receiving treatment was 47% (n=28), including 17 cases of complete remission (28%) and 11 cases of partial remission

The anti-CD79B antibody drug conjugate DCDS0780A can induce deep remission in patients with B-cell non-Hodgkin's lymphoma

Original source:

Alex F.

Leave a message here

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Crocetin27876-94-4

CAS No.: 27876-94-4

$1-1.1/G FOB

Betulinic acid472-15-1

CAS No.: 472-15-1

$1-1.1/G FOB

1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane 53-19-0

CAS No.: 53-19-0

Pharmacy Grade

$100/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.