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Clin Cancer Res: Navumab plus docetaxel significantly prolongs survival in patients treated with ICI and NSCLC

 Last Update: 2022-09-14
 Source: Internet
 Author: User

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The addition of cytotoxic chemotherapy to immune checkpoint inhibitors (ICI) enhances antitumor effects

The study recruited patients with histologically definitive diagnosis of stage IIIB/IIIC/IV or postoperative recurrence who had previously received first- or second-line chemotherapy and were randomly divided into two groups

A total of 128 patients (64 in each group) were enrolled in the overall analysis population

Hematoxicity and gastrointestinal adverse reactions when navumab is combined with docetaxel are more common

Overall, although toxicity is slightly elevated, the addition of docetaxel to navumab significantly prolongs the overall survival and progression-free survival of patients with ICI who have previously been treated with ICI

Original source:

Yuri Taniguchi, Tsuneo Shimokawa, Yuichi Takiguchi, et al.

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