Circulation: One year of exercise can significantly prevent heart failure

Heart failure (HF) is a serious or late stage of various heart diseases

HFpEF is characterized by myocardial stiffness and increased pressure inside the heart during exercise

Left ventricular sclerosis begins in middle age, even if there is no underlying disease, sedentary and aging will make it gradually stiff

Studies have shown that long-term exercise training can improve the heart elasticity of young people, but it has no effect on the heart stiffness of the elderly

However, the heart of middle-aged people still has great plasticity, and its left ventricular myocardial stiffness and biomarkers are between normal and heart failure patients

On September 20, 2021, a research team from the Texas Institute of Sports and Environmental Medicine published a report in the top cardiovascular journal "Circulation" entitled: "One year of persistence in exercise training reverses stage B heart failure with preserved ejection fraction Patients with abnormal left ventricular myocardial stiffness" research paper

The study conducted a one-year exercise test on 46 sedentary middle-aged men and women aged 45 to 64, and found that one year of vigorous exercise training can reduce the stiffness of the left ventricular myocardium

The research team recruited 46 subjects, 31 of whom completed the one-year trial

Twenty people are assigned to individually customized walking, cycling or swimming exercise plans, at least twice a week, at least 30 minutes of high-intensity aerobic interval training, plus 2 to 3 times of medium-intensity training and strength training twice a week

The research team found that the maximum exercise volume of the exercise group (increased from 26.

One year of vigorous exercise training significantly increased the resting stroke volume in the exercise group, while the heart rate dropped from 68±11 beats/min to 64±11 beats/min

The number of resting strokes in the control group was reduced, and there was no significant change in heart rate

In the exercise group, the left ventricular stiffness constant decreased from 0.

The Stalin curve of the control group was comparable at baseline and one year later

In general, this prospective randomized controlled trial found that for middle-aged people with left ventricular hypertrophy and elevated cardiac biomarkers, one year of exercise training can improve physical health and maximum heart rate, left ventricular diastole and myocardium Stiffness, left ventricular hypertrophy and heart damage

High-risk middle-aged men and women perform long-term vigorous exercise training 4 to 5 times a week, which is expected to be a potential intervention to prevent such patients from developing heart failure risks in the future

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