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A new study finds that the nutrient choline -- which has been shown to have long-term benefits for children whose mothers consume it during pregnancy -- also helps the body use omega-3 fatty acids more efficiently, which has a negative effect on the fetal brain, cognitive Knowledge and vision development are critic.
The study was published May 16 in the American Journal of Clinical Nutriti.
The findings suggest that choline supplementation aids cellular metabolism to more efficiently process and release the omega-3 fatty acid DHA in the liver of pregnant wom.
"During pregnancy, the mother is preparing the liver for nutrition and making it available to the baby, so by supplementing with choline and DHA (together), we are increasing DHA bioavailability," said senior author Mary Caudill, professor of nutritional sciences at Health Nair University College of Agriculture and Life Scienc.
These types of nutrient-nutrient interactions are not new, Caudill sa.
Caudill, Cornell University and others have also shown that high maternal choline intake moderates infant responses to stress, improves information processing, and continues to focus on long-term benefits (see study tracking children by age 7), and in pregnant women, choline decreases a factor that causes preeclamps.
For the study, 30 women between 12 and 16 weeks of pregnancy were randomly divided into two groups: one group was given 500 mg of choline per day, and the other was given 50 mg of deuterium-containing choline per day, so that it could be tracked in the bo.
By tracking the labeled choline, the researchers discovered a chemical reaction in which choline donates a small molecule called methyl groups, which are added to a molecule called phosphatidylethanolami.
Future work will help determine whether choline's ability to enhance DHA bioavailability contributes to the benefits of choline supplementation in pregnant wom.
"Our findings suggest that choline supplementation during pregnancy may help achieve higher DHA status at lower DHA doses," Klatt sa.
