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Cholesterol may be the key to new treatments for Alzheimer's disease, diabetes

 Last Update: 2021-04-13
 Source: Internet
 Author: User

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Currently, there is no cure for Alzheimer's disease, which affects more than 5.

Recently, a study published in the journal ACS Pharmacology & Translational Science, health science researchers from the University of Arizona discovered the role of cholesterol in the treatment of Alzheimer’s disease and type 2 diabetes, and found a way to help Small molecules that regulate cholesterol in the brain are expected to become potential targets for the treatment of Alzheimer's disease.

Cholesterol plays a role in the treatment of Alzheimer's disease and type 2 diabetes, and found a small molecule that helps regulate the cholesterol in the brain, which is expected to become a potential target for the treatment of Alzheimer's disease.

Manel Ben Aissa et al, Discovery of Nonlipogenic ABCA1 Inducing Compounds with Potential in Alzheimer's Disease and Type 2 Diabetes, ACS Pharmacology & Translational Science (2021).

"Alzheimer's disease and diabetes have many common causes.

Apolipoprotein E (APOE) is a protein involved in the reverse transport of cholesterol.

Researchers have found that the decreased activity of a cholesterol transporter, ABCA1, is associated with an increased risk of cardiovascular disease, type 2 diabetes, and Alzheimer's disease.

"During the COVID-19 pandemic, we have heard of more and more deaths in nursing homes.

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