Supported by the National Natural Science Foundation of China (project numbers: 3172504, 31970298 and 32000215), Sun Yat-sen University's Xiao Shi group has made progress in the study of the molecular mechanism of phosphatidic acid PA regulating plant hypoxia signal transduction
Hypoxia is one of the most common abiotic stresses that affect plant growth and yield
Studies have shown that ethylene-responsive transcription factor ERF-VII family proteins interact with membrane-associated ACBPs proteins and anchor on the plasma membrane
Genetic, biochemical and lipidomics evidence revealed that MPK3 and MPK6 activated by PA depend on unknown upstream MAPKKK and MKK5, phosphorylate plant hypoxia in response to core transcription factor RAP2.
This study reveals for the first time the new mechanism of plant hypoxia signal chain mediated by PA-MPK3/6-RAP2.
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