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Chinese scholars and overseas collaborators have made progress in the field of organonickel phototherapy research

 Last Update: 2022-08-20
 Source: Internet
 Author: User

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Under the support of the National Natural Science Foundation of China (Grant No.

Photothermal therapy (PTT) combines the advantages of hyperthermia and phototherapy, is not affected by tumor hypoxic conditions, and has the characteristics of photoacoustic diagnosis and treatment

The research team regulates the relative energy levels of the excited state of the metal-to-ligand charge transfer (MLCT) and the excited state of the dd* transition by introducing a "metal-carbon bond" into the macrocyclic ligand, thereby regulating the population and consumption of the excited state.

In this study, organonickel compounds were used as phototherapeutic probes, which provided a new strategy for the molecular design of diagnostic probes and expanded the application of photodiagnosis based on 3d metal-organic compounds

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