Chinese and foreign scholars have revealed the effects of the environment on human gut bacteria and drug-resistant genomes

The team of Professor Liu Yahong of The South China Agricultural University, Lingnan Modern Agricultural Science and Technology Guangdong Province Laboratory and the National Veterinary Microbial Resistance Risk Assessment Laboratory, together with Chinese and foreign partners, found that there are extensive strains and gene exchanges between humans and the environment, and that the environmental impact on human gut microbiomes may last for 4 to 6 months. The study was published online March 18 in Nature -Newsletter.
species of microorganisms in the biosphere, which are everywhere. Similarly, humans have complex microbiomes. The human gastrointestinal tract is an open ecosystem in which microorganisms can be obtained from the external environment, either directly or indirectly. On the other way, the human body continues to release its own microorganisms into the external environment. However, the extent and duration of microbial exchange between the environment and the human gut microbiome is still not well understood.
researchers found that occupational exposure affects the human gut microbiome by integrating techniques such as 16s rRNA sequencing, macrogenomes, and culture groups, leading to the abundance of potential animal pathogens and antibiotic-resistant genes in the gut. Comparing macro genome samples from interns and workers and pig farm environments, it was found that strains and drug-resistant gene exchange were common among interns, workers and the environment. Using dynamic Bayesia network modeling, it was observed that the intestinal bacteria of interns would reverse their pre-internship state four to six months after returning to school, but some drug-resistant genes would remain in the human gut.
large number of microorganisms in the breeding environment, which often becomes a hot spot for the exchange of bacteria and drug-resistant genes. Liu Yahong said changes in the human living environment can continue to shape the human gut bacteria and drug-resistant genome. With the rapid development of next-generation sequencing technology, through the combination of traditional technology, in the analysis of unknown scientific issues issues issues issues of great vitality. (Source: Zhu Hanbin Fangxuan, China Science Journal)