China approves Roche's white cell interlocutoryin-6 monoantia to control inflammatory storms in patients with new coronavirus infection
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Last Update: 2020-05-29
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Source: Internet
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Author: User
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China has approved the use of Roche's anti-inflammatory drug Actemra (tocilizumab), a monoantigen that targets leukade 6, in patients with coronavirus with lung complicationsprevious studieshave shown that the level of IL-6 inbloodis significantly elevated, and that elevated levels of IL-6 (inflammation and high levels ofimmunodeficiency biomarkers of immuneresponse) are associated with increased mortality in patients with new coronavirusinfectionpneumoniaActemra's approval is due to the drug's ability to suppress cytokine release syndrome (CRS), an out-of-control form of systemic inflammatory response that may be a complication of certain diseases or infectionsActemra was initiallyThe FDAapproved as a treatment for rheumatoid arthritis, and subsequently approved for the treatment of juvenile isoarthritis, cytomegaloy teritis, and CRS associated with cancer CAR-T cell therapyActemra is now included in the new treatment guidelines for COVID-19 issued by the National Health councilearlier this weekRoche said it had donated nearly $2 million worth of Actemra to China to help control the COVID-19 outbreakthere is no efficacy or safety data to support Actemra's use in PATIENTs infected with COVID-19, Chinese researchers are conductingclinicaltrials of 188 patients infected with the virusPreliminary results from 14 patients suggest the drug may be helpful to patients with severe lung disease infections
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