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A new study that analyzed the genetic data of more than 400,000 people found that being overweight in childhood increases the risk of developing type 1 diabetes later in life
The number of people diagnosed with type 1 diabetes has increased dramatically over the past 20 years
Compared with type 1 diabetes, there is irrefutable evidence that overweight children are more likely to develop type 2 diabetes and that weight loss can lead to sustained remission
The researchers analysed human genetic data from 454,023 individuals from the UK Biobank and 15,573 cases of type 1 diabetes from other cohorts, and applied a scientific technique called Mendelian randomisation (MR) to provide evidence that children Obesity increases the risk of type 1 diabetes
By applying this technology, the findings support the inference that early obesity increases an individual's risk of developing type 1 diabetes, and that the growing prevalence of childhood obesity may contribute to an increase in type 1 diabetes cases
Dr Tom Richardson, a researcher in the Bristol Medical Council's Integrative Epidemiology Group and Population Health Sciences at Bristol Medical School and lead author of the study, said: "The impact of childhood obesity directly increases the incidence of type 1 diabetes.
"There is a critical window in childhood that can mitigate the impact of obesity on the increasing number of Type 1 diabetes diagnoses