Chickpea can extract antitumor protein and polypeptide

The reporter recently learned from Xinjiang Institute of physical and chemical technology, Chinese Academy of Sciences that the researchers of the Resource Chemistry Research Office of the Institute have developed a method to extract natural anti-tumor protein and polypeptide from the bean flap of chickpea Relevant research results have been authorized by national invention patent recently At present, tumor has become the second largest killer after cardiovascular and cerebrovascular diseases It has become one of the hot spots in the world to find high-efficiency and low toxicity anti-tumor drugs Bioactive peptides are a kind of multifunctional compounds that exist naturally in animals, plants and microorganisms Bioactive peptides can also be obtained from animal and plant proteins by proteolysis, artificial chemical synthesis and bioengineering At present, hundreds of peptides have been found in vivo, which are essential participants in the complex physiological activities of the body Chickpea belongs to the pea nationality of Leguminosae, which has a 2500 year history in Xinjiang It is a commonly used medicine in Uyghur medicine It has been collected in the Uyghur medicine standard and Uyghur medicine record of the Ministry of health Although chickpea has a long history of drug use, its functional factors are not clear, especially the study of bioactive peptides is still blank The method of extracting natural anti-tumor protein and polypeptide from chickpea flap developed in this research and development can obtain the protein and polypeptide that can inhibit the activity of colon cancer cells through the steps of phosphoric acid buffer solution extraction, ammonium sulfate precipitation, desalination and centrifugation This provides a basis for the basic research of bioactive substances and the corresponding product development of Uighur medicine and food plant chickpea According to the researchers, this method is simple in extraction process, and it is not easy to inactivate proteins and peptides The prepared peptides have high biological activity, non toxicity, good thermal stability, easy to expand production scale, and can reduce the cost of extraction process It is one of the ideal methods for extracting and preparing bioactive proteins and peptides The protein and polypeptide obtained by the method can be used for preparing functional food or pharmaceutical additives.