Chest: Sleep disorders and cognitive changes after severe illness.

Survivors of the !---- Intensive Care Unit (ICU) may experience cognitive impairment and persistent sleep disorders after hospitalization.sleep disorders have been associated with cognitive impairment in various patient groups, while lipoprotein E (APOE) genotypes have been associated with sleep-related cognitive impairment., a study published in the journal Chest, an authoritative journal of the field of respiratory sciences, aims to clarify whether there is a link between sleep, long-term cognition and APOE status of ICU survivors. The researchers recruited 150 patients from five centers who received mechanical ventilation for at least three days.102 patients survived until the ICU was discharged.conduct editing and cognitive tests 7 days, 6 months and 12 months after the ICU is discharged from the hospital, and estimate sleep time, quality, and time through activity records.researchers tested each patient's APOE single nucleotide polymorphism.at the 7 days of discharge from the ICU, the estimated sleep disorder seamount from the active record rather than the total sleep time or daily stability (estimated circadian rhythm) was associated with more severe cognitive impairment.7 days after discharge from the ICU, no activity recorded estimated sleep estimate variables that predicted cognitive impairment or persistent sleep disorders in survivors at 6 and 12 months of follow-up.a significant correlation between the APOE 4 allenocis and sleep disorders, and their presence did not alter the risk of sleep-related cognitive impairment during follow-up.it follows that sleep disorders estimated through activity records are associated with poor cognitive performance.further research is needed to better describe the relationship between persistent sleep disorders and the cognition of ICU survivors..