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Cheng Zhukuan's research group has made important progress in the assembly of meiotic synaptic complexes

 Last Update: 2021-11-14
 Source: Internet
 Author: User

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Synaptic complex assembly is an important event that occurs between paired homologous chromosomes in the process of meiosis, and plays a vital role in ensuring the correct conduct of homologous recombination

Cheng Zhukuan's research group at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences used map-based cloning technology to identify a new synaptic regulatory gene DESYNAPSIS1 ( DSNP1 )

The study in 2021 Nian 11 Yue 2 Ri in Cell Reports published online in the journal

Figure: Super-resolution microstructure of wild-type and dsyn1 mutant synapse complex

ZEP1 is the central element of the syndicate complex , and PAIR3 is the lateral element of the syndicate complex

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