Chemicals are expected to erase traumatic memories: saving patients with depression and anxiety

It is difficult to erase the imprint of traumatic experience in the brain, which makes the treatment of PTSD very difficult But if memory can be changed, perhaps some day those suffering from phobia, post-traumatic mental disorder and other anxiety disorders will be cured In recent years, scientists in the United States and Canada have made a lot of progress in the field of chemical therapy to alleviate traumatic memory Key nerve cells for long-term memory processing (source: Peking University new media) US scientists have found a new target for PTSD drugs A few days ago, researchers from Perelman Medical College at the University of Pennsylvania have found that a key enzyme is the core of the brain for storing long-term memory, which can turn genes on or off when new memories are formed In mouse experiments, it was shown that if the level of acss2 decreased, long-term memory could not be recalled This study provides new drug targets for diseases such as anxiety and depression Chemicals are injected directly into the brain to clean unpleasant memories Scientists from Massachusetts Institute of technology and New York State University have developed a chemical called zip, which can completely disable the learning process that forms memories In mice, they injected the drug directly into the brain The results showed that zip could weaken the connections between the cells in the hippocampus of the mouse brain, so as to clean part of the memory of the mouse However, because zip has an overall effect on memory and lacks selectivity, it is unlikely to be used in human body in a short period of time as a specific drug to eliminate negative memory However, if you can prevent zip from entering the brain through chemical modification and only play a role in the spinal cord, zip may become a good medicine Psychedelic mushrooms (source: Flickr) magic mushrooms help patients get rid of anxiety and depression According to a study conducted by Johns Hopkins University in the United States, there are mushrooms in nature called hallucinogenic mushrooms, which contain a compound called psilocybin, which can make people dream When PTSD patients recall traumatic memory, the use of gavelin can guide the brain activity of patients into dreams to treat their anxiety and depression Propranolol (source: Wikipedia) Propranolol, a non selective competitive inhibitor of adrenergic β receptor, can block β 1 and β 2 receptors in the heart, antagonize sympathetic excitation and catecholamine action, and reduce the contractile force and contractile speed of the heart It is commonly used in the treatment of angina pectoris and hypertension Scientists from McGill University in Canada and Harvard University in the United States used propranolol to suppress the negative emotions of trauma patients when recalling trauma, and other memories were not affected Don't eat cinnamon in the cinnamon mice experiment (source: Jerry daliege), it will only make the memory more and more firm Scientists at Rush University found that sodium benzoate is one of the products of cinnamon decomposition in vivo Sodium benzoate can enhance the structural integrity of brain cells, making neurons more closely linked Dr pahan, the project leader, fills a spoonful of cinnamon powder (about 3.5G) every day and takes it with honey as a tonic Because his mouse experiments showed that long-term administration of sodium benzoate can improve the memory ability of mice by 150%.