CFDA reminds attention to serious adverse reactions of cefazolin injection

According to the website of the State Food and drug administration, the State Food and Drug Administration recently released the 59th issue of adverse drug reaction information notice, reminding people of the serious adverse drug reactions of cefazolin injection Cefazolin, a broad-spectrum β - lactam antibiotic, is the first generation of cephalosporin for injection The drug has strong antibacterial effect on most sensitive gram-positive cocci and common gram-negative bacilli At present, there are two kinds of cefazolin injections approved in China: cefazolin sodium for injection and cefazolin sodium pentahydrate for injection In 2013, the national ADR case report database received 349 serious case reports of cefazolin injection The most serious adverse reactions were anaphylactic shock and severe anaphylactic reaction At the same time, the problem of unreasonable use of cefazolin injection still exists, especially in the case of over indication and single dose Relevant cephalosporin Research Report 2014-2015 global cephalosporin industry market survey and investment forecast analysis report 2014-2015 global cephalosporin industry market survey and investment forecast analysis study 2013-2018 global cephalosporin industry market depth analysis and investment profit value forecast report 2013-2018 global cephalosporin industry market depth analysis and investment Profit value forecast 2013-2018 global 7-amino-3-methoxymethyl-3-cephem-4-carboxylic acid industry market deep more pharmaceutical industry analysis according to case report database information analysis, State Food and Drug Administration prompt: 1 The relevant pharmaceutical manufacturers shall modify and improve the relevant contents of the manual in combination with the actual varieties, strengthen the monitoring of adverse drug reactions after the listing, do a good job in the publicity and training of safe drug use, and guide the clinical rational drug use 2 Medical staff pay attention to the serious adverse reactions and clinical rational use of cefazolin injection, use it in strict accordance with the drug instructions, avoid the use of super indications, avoid the excessive dosage of single use, etc It is suggested that grass-roots medical institutions should strengthen the training of medical staff on clinical medication and first aid knowledge, promote the rational use of antibiotics, and ensure the safety of public medication.