 Home > Biochemistry News > Biotechnology News > CELL MOL LIFE SCI Ji Xiong's research group reveals the functional mechanism of BRD2-mediated RNA polymerase II transcription

CELL MOL LIFE SCI Ji Xiong's research group reveals the functional mechanism of BRD2-mediated RNA polymerase II transcription

 Last Update: 2022-08-20
 Source: Internet
 Author: User

Tags

cell freezing container

pa chip application

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

BRD2/3/4/T are members of the BET protein family in mammalian cells.

On June 4, 2022, Ji Xiong's group from the School of Life Sciences and the Life Center of Peking University published an online article entitled "BRD2 interconnects with BRD3 to facilitate Pol II transcription initiation and elongation to prime promoters for cell differentiation" in the journal Cellular and Molecular Life Sciences research paper

In this work, the authors first established an embryonic stem cell line that transiently degrades BRD2 protein.

Based on the above findings, the authors further explored the physiological significance of BRD2 regulation of Pol II transcription using mouse embryonic stem cell in vitro differentiation and multi-omics techniques

Figure 1.

Ji Xiong, a researcher from the School of Life Sciences and the Life Center of Peking University, and Huang Jie, a postdoctoral fellow, are the co-corresponding authors of the paper

Article link: https://link.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.