"Cell" important breakthrough!

The microbes in our bodies affect physiological functions all the time.

What most current studies have found is that microbes exist to regulate cancer susceptibility and tumor progression

With the development of sequencing technology, some scientists in Israel and the United States have shown that microbes not only indirectly affect tumors, but are more likely to be part of tumors

▲Intracellular bacteria of tumors can help them metastasize (Image source: Reference [2])

In the new study, Dr.

Even more surprising, many of these bacteria colonized the cytosol of cancer cells, the interior of the cell

▲Antibiotic clearance experiments have shown that tumor flora is crucial for tumor metastasis (Image source: Reference [2])

They observed that when cancer cells roamed the circulatory system, the bacteria traveled with them throughout the body

In research tests, the bacteria in the cancer cells appeared to specifically help the cancer cells to metastasize, while having little effect on the growth of in situ tumors

▲ Tumor cells carry bacteria to distant organs and promote metastasis (Image source: Reference [2])

The study managed to collect tumor microbiota in peripheral blood.

And one of the most important things bacteria do in metastasis is to help cancer cells resist mechanical stress.

This "symbiotic" relationship is really amazing.

Although studies have confirmed that intracellular bacteria play an important role in cancer metastasis, the research team does not rule out the possibility that these bacteria influence the progression of cancer in situ

We may be more concerned about whether this research can help us resist and treat tumors? Dr.

Note: The original text has been deleted

References:

[1] Evidence in mice that bacteria in tumors help cancer cells metastasize.

[3] Nejman, D.

[4] Riquelme, E.

[5] Jin, C.