Cancers: Prognostic value of adjuvant chemotherapy in patients with mucinous colorectal adenocarcinoma without distant metastasis

existIn colorectal cancer , the prognosis of patients with mucinous adenocarcinoma (MAC) is worse than that of adenocarcinoma (AC)
.

However, the prognostic indicators of mucinous adenocarcinoma (MAC) remain controversial

existIn colorectal cancer , the prognosis of patients with mucinous adenocarcinoma (MAC) is worse than that of adenocarcinoma (AC)

The study included 22,779 patients, of whom 22,050 (96.
8%) and 729 (3.
2%) were in the AC and MAC groups, respectively
.

The median follow-up time was 54.

The study included 22,779 patients, of whom 22,050 (96.

Multivariate prognostic analysis found that risk factors were similar between the two groups
.

However, low and high BMI were significant risk factors for AC, but not for MAC .

Multivariate prognostic analysis found that risk factors were similar between the two groups

The OS of the MAC group was worse than that of the AC group (5-year OS rate: 79.

4 vs.
70.
0%, p<0.
001); there was no significant difference in OS between the two groups in patients with stage I, IIA, and IIB/C

The OS of the MAC group was worse than that of the AC group (5-year OS rate: 79.

Using the propensity-matched score, OS in both groups was more consistent with the initial analysis
.

Using propensity-matched scores, OS in both groups was more consistent with the initial analysis
.

Using propensity-matched scores, OS in both groups was more consistent with the initial analysis

In conclusion, studies have shown that the prognosis of patients with mucinous adenocarcinoma (MAC) is worse than that of adenocarcinoma (AC) patients, especially in stage III patients, and adjuvant chemotherapy does not significantly improve the prognosis of patients
.

In conclusion, studies have shown that the prognosis of patients with mucinous adenocarcinoma (MAC) is worse than that of adenocarcinoma (AC) patients, especially in stage III patients, and adjuvant chemotherapy does not significantly improve the prognosis of patients
.

Studies have shown that the prognosis of mucinous adenocarcinoma (MAC) patients is worse than that of adenocarcinoma (AC) patients, especially in stage III patients, and adjuvant chemotherapy does not significantly improve the prognosis of patients

Original source:

Bong JW, Gim JA, Ju Y, Cheong C, Lee SI, Oh SC, Min BW, Kang S.
Prognosis and Sensitivity of Adjuvant Chemotherapy in Mucinous Colorectal Adenocarcinoma without Distant Metastasis.
Cancers (Basel).
2022 Mar 2;14(5 ): 1297.
doi: 10.
3390/cancers14051297.
PMID: 35267605.

Bong JW, Gim JA, Ju Y, Cheong C, Lee SI, Oh SC, Min BW, Kang S.
Prognosis and Sensitivity of Adjuvant Chemotherapy in Mucinous Colorectal Adenocarcinoma without Distant Metastasis.
Cancers (Basel).
2022 Mar 2;14(5 ): 1297.
doi: 10.
3390/cancers14051297.
PMID: 35267605.
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