Cancer: Surprise discovery! Vitamin D makes immunotherapy safer! Significantly reduce the toxic side effects of immune checkpoints!

, July 7, 2020 /
PRNewswire/ -- Taking vitamin D supplements may help prevent serious side effects that a revolutionary anti-cancer treatment can haveThe findings were published in cancer, a peer-reviewed journal of the American Cancer Society (ACS)immunological checkpoint inhibitors help the immune system identify and fight cancer cells, and while these treatments help many patients and prolong their lives, they can also cause side effects such as colitis, an inflammatory colon responseColitis caused by immunocheckpoint inhibitors can limit the use of these life-saving drugs, leading to the termination of treatmentAlthough it is one of the most common and serious adverse events in immunotherapy, there is a lack of understanding of the risk factors that can improve the prevention of colitisPhoto Source: DrDrAnd his colleagues conducted a study to study whether taking vitamin D supplements may reduce the risk of colitis in patients who receive immunoostine inhibitors for cancer treatmentThe team chose this strategy because previous studies have found that vitamin D may affect the immune system in the context ofautoimmunediseases and inflammatory bowel diseasethe study included information on 213 patients who were treated with immunoospha inhibitorsmelanomabetween 2011 and 2017Of these, 37 (17%) developed colitis Sixty-six patients (31%) who participated in the study took vitamin D supplements before receiving immunoosine inhibitor stakes patients who took vitamin D had a 65 percent lower risk of developing colitis after adjusting for mixed factors The findings were validated in another group of 169 patients, 49 (29%) of whom developed colitis In this validation group, vitamin D was used to reduce the chance of colitis by 54% "If confirmed in future prospective studies, our findings on a link between vitamin D intake and reduced colonitis risk may have an impact on practice," said Dr Rahma Vitamin D supplementation should be further tested to determine whether it is a safe, accessible and cost-effective method to prevent gastrointestinal toxicity in immunotherapy and to expand the effectiveness of immunocheckpoint inhibitor therapy in cancer patients "(BioValleyBioon.com) References: "
Vitamin D Intake is the of the Vitamin D Intake with D-D Risk of The D-Rain- Andre Checkpoint-Induced Collitis." Cancer (2020) DOI: 10.1002/cncr.32966
vitamin D May help a common side effect of anti-cancerthese eith