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Cancer Cell: Analysis of rare susceptibility mutations in lung cancer based on genome-wide analysis of 6,004 Chinese

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Research Highlights:

We conducted the largest non-small cell lung cancer (NSCLC) whole genome sequencing (WGS) study to date, with 6,004 Chinese individuals and 23,049 individuals

We presented the largest non-small cell lung cancer (NSCLC) whole genome sequencing (WGS) study to date in 6,004 individuals of Chinese ancestry, and 23,049 individuals

For the rare loss of function (LoF) variant (MAF < 0.

These associations were validated

Original Source:

Wang C, Dai J, Qin N, Fan J, Ma H, Chen C et al.

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