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A new study from the Institute of Systems Biology (ISB) shows that the closest link to the success or failure of weight loss, not BMI, is found in the genetic ability of the gut microbiota
.
The closest link to the success or failure of weight loss (not related to BMI) is found in the genetic ability of the gut microbiota
.
These new findings open the door to diagnostic tests that can determine who may lose weight through healthy life>
ISB researchers surveyed 105 people who participated in consumer health programs
.
Approximately half of the cohort showed sustained weight loss and improvement in metabolic health indicators
"Our research results underscore the fact that our gut microbiota is an important filter between our food and blood
.
The lead author of this paper, Dr.
Importantly, the team studied the determinants of successful weight loss, which have nothing to do with BMI
.
People with a higher baseline bmi tend to lose more weight after receiving the intervention—a condition known as the “return to mean” effect
Researchers have found that certain specific bacteria (Prevotella and other Bacteroides) seem to be more effective in using the degradation products of complex starch and fiber to promote growth, which may be used in obtaining these energy-rich small molecules.
Overcome the body and reduce the calories gained from the food you eat
.
Ensuring that our gut microbes can effectively convert sugars separated from dietary fiber into short-chain fatty acids and/or reducing the abundance of bacterial fiber degradation genes in the intestine may help to ensure an improved weight loss response under life>
ISB Assistant Professor Dr.
Sean Gibbons, the corresponding author of the paper, said: “At least, this work may lead to a diagnosis to determine who will respond well to moderately healthy life>
.
” “By understanding which microbes and metabolic processes help promote weight loss in the gut microbiota, we can begin to design targeted prebiotics and probiotic interventions that may promote weight loss resistant microbiota looks like It’s more like a weight-loss license microbiome
references:
"Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Life>mSystems .
DOI: 10.
1128/mSystems.
