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*For medical professionals only
To avoid dosing errors that can lead to accidental overdose and death, caution should be exercised when prescribing, preparing, and administering acetaminophen
injections.
Acetaminophen injection contains acetaminophen
.
Acetaminophen is associated with cases of acute liver failure and sometimes leads to liver transplantation and death
.
Most cases of liver injury are associated with daily use of this product exceeding the maximum daily limit and usually involve more than one product
containing acetaminophen.
(1) If the symptoms persist, the drug can be repeated once at intervals of 4-6 hours, and no more than 4 times within 24 hours
.
(2) For infants and children, drops, suspensions, syrups and other dosage forms suitable for infants and young children are preferred to avoid the risk of
choking due to swallowing before the drug is completely disintegrated.
If using this product, the tablet must be completely dissolved with a small amount of water before taking it, and it should be used
under adult supervision to ensure that there is no risk of choking.
(3) For the treatment of acute pain or fever, acetaminophen injection can be administered
single or repeatedly.
Adults and adolescents weighing 50 kg and older do not need to adjust the dose
when switching between oral and injectable paracetamol.
The maximum daily dose of paracetamol is based on all routes of administration (i.
e.
, intravenous, oral, and rectal) and all products containing paracetamol
.
When used daily in doses exceeding the maximum daily dose of paracetamol, it may lead to liver damage, including the risk of
liver failure and death.
To avoid the risk of overdose, ensure that the total amount of paracetamol from all routes and sources does not exceed the maximum recommended dose
.
Granules, tablets, capsules: 0.
3-0.
6g at a time, 3-4 times a day as needed, the daily dosage should not exceed 2g
.
Analgesic treatment should not exceed 10 days, and this product should not be taken for a long time [1].
Sustained-release tablets: 0.
65-1.
3g at a time, if symptoms persist, once every 8 hours, no more than 3 times
in 24 hours.
[2]
Suppositories: rectal administration, once 0.
3 g
.
Chewable tablets: swallow after chewing, 0.
32-0.
48 g
at a time.
Injection: intramuscular injection, once 0.
15g-0.
2g, this product should not be used for long-term use, analgesic treatment should not exceed 10 days
.
Oral collapse tablets: oral, this product does not need water or only a small amount of water, and does not need to chew, the drug is placed on the tongue, quickly disintegrated, by swallowing into the digestive tract to take effect, once 0.
24-0.
48g
.
What should I do if a patient has a high fever while on emergency duty? Finding the cause is the most important thing! How to deal with emergencies is correct?
Severe allergic reaction rescue, is epinephrine preferred? How is it administered? Where to see the flow chart, treatment points, and summary of the most complete emergency drugs?
Open "Clinical Decision Assistant - Evidence-based Medicine"
to search for related disease names/drug names, and go directly to what you want to see with one click, all here! 👇
Drug information: acetaminophen tablets, Sanofi (Hangzhou) Pharmaceutical Co.
, Ltd.
, Sinopharm H33021739; 2015/12/01.
[2].
Drug information: acetaminophen sustained-release tablets, Chengdu Hengrui Pharmaceutical Co.
, Ltd.
, Sinopharm H19990360; 2012/10/31.
▼▼▼Click to read the original article to download the app
For more common drugs in the emergency department, go to the "Clinical Decision Assistant App"!
The intensity of acetaminophen's antipyretic effect is similar to aspirin, and it plays an analgesic effect by inhibiting the synthesis and release of prostaglandins, etc.
, raising the pain threshold, and belongs to peripheral analgesics
.
As a recent "hot player", many people have not yet bought it
even if they have already "Yangkang".
With the liberalization of epidemic policies and the implementation of prevention and control measures for everyone, we must not only learn to buy medicines but also learn to use them safely for the health of ourselves and our families
.
Is acetaminophen associated with cases of acute liver failure? These acetaminophen medication points that you need to know even if you are yang kang take a look together!
Medication errors and risk of hepatotoxicity
To avoid dosing errors that can lead to accidental overdose and death, caution should be exercised when prescribing, preparing, and administering acetaminophen
injections.
Acetaminophen injection contains acetaminophen
.
Acetaminophen is associated with cases of acute liver failure and sometimes leads to liver transplantation and death
.
Most cases of liver injury are associated with daily use of this product exceeding the maximum daily limit and usually involve more than one product
containing acetaminophen.
Exceeding the maximum daily dose may lead to liver damage
(1) If the symptoms persist, the drug can be repeated once at intervals of 4-6 hours, and no more than 4 times within 24 hours
.
(2) For infants and children, drops, suspensions, syrups and other dosage forms suitable for infants and young children are preferred to avoid the risk of
choking due to swallowing before the drug is completely disintegrated.
If using this product, the tablet must be completely dissolved with a small amount of water before taking it, and it should be used
under adult supervision to ensure that there is no risk of choking.
(3) For the treatment of acute pain or fever, acetaminophen injection can be administered
single or repeatedly.
Adults and adolescents weighing 50 kg and older do not need to adjust the dose
when switching between oral and injectable paracetamol.
The maximum daily dose of paracetamol is based on all routes of administration (i.
e.
, intravenous, oral, and rectal) and all products containing paracetamol
.
When used daily in doses exceeding the maximum daily dose of paracetamol, it may lead to liver damage, including the risk of
liver failure and death.
To avoid the risk of overdose, ensure that the total amount of paracetamol from all routes and sources does not exceed the maximum recommended dose
.
Different dosage forms are used differently?
Granules, tablets, capsules: 0.
3-0.
6g at a time, 3-4 times a day as needed, the daily dosage should not exceed 2g
.
Analgesic treatment should not exceed 10 days, and this product should not be taken for a long time [1].
Sustained-release tablets: 0.
65-1.
3g at a time, if symptoms persist, once every 8 hours, no more than 3 times
in 24 hours.
[2]
Suppositories: rectal administration, once 0.
3 g
.
Chewable tablets: swallow after chewing, 0.
32-0.
48 g
at a time.
Injection: intramuscular injection, once 0.
15g-0.
2g, this product should not be used for long-term use, analgesic treatment should not exceed 10 days
.
Oral collapse tablets: oral, this product does not need water or only a small amount of water, and does not need to chew, the drug is placed on the tongue, quickly disintegrated, by swallowing into the digestive tract to take effect, once 0.
24-0.
48g
.
Where to learn more about emergency care?
What should I do if a patient has a high fever while on emergency duty? Finding the cause is the most important thing! How to deal with emergencies is correct?
Severe allergic reaction rescue, is epinephrine preferred? How is it administered? Where to see the flow chart, treatment points, and summary of the most complete emergency drugs?
Open "Clinical Decision Assistant - Evidence-based Medicine"
to search for related disease names/drug names, and go directly to what you want to see with one click, all here! 👇
Download the Decision Assistant App and check it anytime, anywhere~
References: [1].Drug information: acetaminophen tablets, Sanofi (Hangzhou) Pharmaceutical Co.
, Ltd.
, Sinopharm H33021739; 2015/12/01.
[2].
Drug information: acetaminophen sustained-release tablets, Chengdu Hengrui Pharmaceutical Co.
, Ltd.
, Sinopharm H19990360; 2012/10/31.
▼▼▼Click to read the original article to download the app
