Brit J Heamatol: Immune platelet reduction in child and adolescent fatigue
-
Last Update: 2020-07-12
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
Immuneplatelet reduction disorder (ITP) is an acquired low platelet autoimmune disease with a risk of bleeding and a significant impact on health-related quality of life (HRQoL)ITP patients often report significant fatigue, although little is known about this pathophysiological mechanismrecently published a study in the journal British Journal of Haematology, an authoritative journal for blood system diseases, in which researchers evaluated fatigue reports using the Hockenberry Fatigue Scale in observational queues of 120 ITPschildren who received second-line treatmentItP children and adolescents reported similar levels of fatigue, with 54 per cent (29/54) children and 62 per cent (26/42) adolescents reporting moderate to severe fatigueThere was no correlation between fatigue and age or genderThe average fatigue score for adolescents withand persistent ITPs in the newdiagnosis is higher than that of chronic ITP (P s 0.03)One month after the start of second-line treatment, fatigue improved significantly in children and adolescents, and the improvement continued for 12 months after the start of treatmentFatigue scores at all points in time were associated with general HRQoL assessed using the Kids ITP tool, but were not related to bleeding symptoms, platelet counts, or platelet response to treatmentthus shows that fatigue is common in ITP children and adolescents and can benefit from ITP-directed treatment even if there are no bleeding symptoms
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
