Brit J Heamatol: Acute kidney injury in children with sickle cell disease is related to disease and use of medical resources
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Last Update: 2020-06-24
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Source: Internet
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Author: User
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Kidney disease is a common complication in patients with sickle cell disease (SCD), although the epidemiology of acute kidney injury (AKI) in pediatric patients and its effect on long-term kidney outcomes is not yet known, researchers used the Paediatric Health Information System (PHIS) to identify SCD pediatric patients admitted to hospital for vascular insemination (VOC) in a study published in the journal British Journal of Blood System Diseasesoverall, 1.4% of patients experienced at least one AKI attack, while 2.5% were admitted to hospital with concurrent AKIPatients who have AT least one EPISODE of AKI at first admission are more likely to be adolescents or young adults, with increased admission rate, longer hospital stays, increased hospital costs, increased risk of readmission, and an increased incidence of SCD-related complicationsThe broad estimation equation model shows that the history of old age, hypertension, hematuria and chronic renal history are associated with an increased risk of Aurise, although the use of hydroxyurea has a protective effect (OR is 0.64, 95% CI is 0.44-0.94)it is thus possible that AKI seizures during hospitalization of children with SCD are associated with increased use of disease and medical resources, and the use of hydroxyurea can reduce the likelihood of this complication
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