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Brit J Cancer: The significance of the ratio of neutrophils to lymphocytes to the prognosis and diagnosis of patients with hepatocellular carcinoma

 Last Update: 2021-06-21
 Source: Internet
 Author: User

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Neutrophil-lymphocyte ratio (NLR) is a putative indicator that measures the balance between neutrophil-related pre-tumor inflammation and lymphocyte-dependent anti-tumor immune function.
It has been considered to include hepatocellular carcinoma (HCC).
), including several prognostic indicators of cancer
.

immunity

Recently, a research article was published in the British Journal of Cancer, an authoritative journal in the field of oncology.
In this study, researchers included 781 patients (493 cases of hepatocellular carcinoma and 288 cases of chronic liver disease without hepatocellular carcinoma).
The prospective cumulative cohort was followed up for more than 6 years
.

The researchers compared the NLR levels between patients with liver cancer and chronic liver disease, and assessed the impact of baseline NLR on the overall survival of patients with liver cancer through multivariate Cox regression analysis
.

Survival curve

At the beginning of the study (baseline), there was no clinically significant difference in NLR values between patients with chronic liver disease and HCC patients
.

Among HCC patients, the NLR level closest to the last visit/death was significantly higher than the baseline level

It can be seen that NLR is an important independent factor affecting the survival of HCC patients

NLR is an important independent factor affecting the survival of HCC patients

Original source:

Philip J.

The prognostic and diagnostic significance of the neutrophil -to-lymphocyte ratio in hepatocellular carcinoma: a prospective controlled study in this message

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